Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18770659 | 0.81 | CA12 (0.38) | LMNAGAAMAPK1MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL18770629 | 0.79 | ALDH1A1 (0.40) | LMNAGAAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL22831837 | 0.77 | TSHR (0.44) | ACHELMNAMAPTTSHRALDH1A1 | |
| SCHEMBL3228491 | 0.74 | ALDH1A1 (0.52) | ACHELMNAGAAMAPK1MAPT | |
| SCHEMBL8056786 | 0.73 | ACHE (0.52) | ACHELMNAGAAMAPK1MAPT | |
| SCHEMBL8761590 | 0.73 | ACHE (0.52) | ACHELMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL8117764 | 0.72 | ACHE (0.56) | ACHELMNAGAAMAPK1MAPT | |
| SCHEMBL3226790 | 0.72 | CA1 (0.32) | ALDH1A1 | |
| SCHEMBL3973574 | 0.72 | ACHE (0.56) | ACHELMNAGAAMAPK1MAPT | |
| SCHEMBL8113473 | 0.71 | L3MBTL1 (0.41) | LMNAGAAMAPK1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2149552-A1 | 5,6 substituted benzamide derivatives as modulators of EP2 receptors | Bayer Schering Pharma AG (DE) | 2010-02-03 | — | — | EP | disclosed |