Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 5/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3287319 | 0.92 | PAX8 (0.38) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL994780 | 0.78 | PAX8 (0.38) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| Hydrochloric Acid SCHEMBL25188851 | 0.77 | PAX8 (0.37) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL23840 | 0.74 | ALDH1A1 (0.47) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL5313840 | 0.74 | ALDH1A1 (0.47) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL27337795 | 0.74 | HPRT1 (0.54) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| SCHEMBL11504266 | 0.72 | HPRT1 (0.45) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| Ethylene Glycol SCHEMBL18525382 | 0.69 | ALDH1A1 (0.41) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| Ethylene SCHEMBL28814532 | 0.67 | HPRT1 (0.88) | HPRT1PAX8ALDH1A1TDP1HSD17B10 | |
| Chrysene SCHEMBL27115 | 0.67 | HPRT1 (1.00) | HPRT1PAX8ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100068302-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | TRASLATIONAL CANCER DRUGS PHARMA, S.L. (ES) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100068302-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER | ASAH1, ACER2, ASAH2 | HPRT1 981/4885PAX8 4487/4885ALDH1A1 1928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.