Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP7 | O15540 | 4/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3386517 | 1.00 | FABP7 (0.55) | FABP7FABP5TSHRALDH1A1TDP1 | |
| SCHEMBL830680 | 0.82 | TSHR (0.55) | TSHRALDH1A1MAPK1KMT2A | |
| SCHEMBL830682 | 0.82 | TSHR (0.55) | TSHRALDH1A1MAPK1KMT2A | |
| SCHEMBL835776 | 0.82 | TSHR (0.55) | TSHRALDH1A1MAPK1KMT2A | |
| SCHEMBL13778720 | 0.80 | TSHR (0.57) | FABP7FABP5TSHRALDH1A1TDP1 | |
| SCHEMBL3142879 | 0.80 | TSHR (0.57) | FABP7FABP5TSHRALDH1A1TDP1 | |
| SCHEMBL23464707 | 0.76 | ALDH1A1 (0.50) | FABP7FABP5TSHRALDH1A1TDP1 | |
| SCHEMBL23342969 | 0.76 | ALDH1A1 (0.50) | FABP7FABP5TSHRALDH1A1TDP1 | |
| SCHEMBL6739703 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1TDP1LMNA | |
| SCHEMBL26349770 | 0.75 | TSHR (0.52) | FABP7FABP5TSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904515-B1 | SIDE-CHAIN EXTENDED LIGATION | AMYLIN PHARMACEUTICALS INC (US) | 2010-12-08 | — | — | EP | disclosed |
| US-20090192300-A1 | Side-Chain Extended Ligation | GENEPROT INC. (CH) | 2009-07-30 | — | — | US | disclosed |
| EP-1904515-A1 | SIDE-CHAIN EXTENDED LIGATION | Amylin Pharmaceuticals, Inc. (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006133962-A1 | SIDE-CHAIN EXTENDED LIGATION | AMYLIN PHARMACEUTICALS, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192300-A1 | Side-Chain Extended Ligation | CTH, BCAT1, LNPEP | FABP7 2311/4885FABP5 2087/4885TSHR 1881/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.