Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 15/20 | 0.41 |
| ▸ | FGFR3 | P22607 | 14/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3385303 | 0.81 | FGFR3 (0.48) | KDRFGFR3RIPK2RAF1 | |
| SCHEMBL3385688 | 0.71 | PIK3CA (0.46) | KDRFGFR3PIK3CAMTORRAF1 | |
| SCHEMBL3386414 | 0.70 | RAF1 (0.58) | KDRFGFR3RIPK2RAF1 | |
| SCHEMBL3385983 | 0.70 | KDR (0.47) | KDRFGFR3RIPK2RAF1 | |
| SCHEMBL3385159 | 0.69 | FGFR3 (0.34) | KDRFGFR3PIK3CAMTOR | |
| SCHEMBL3381118 | 0.69 | NPC1 (0.54) | KDRFGFR3RAF1 | |
| SCHEMBL3381856 | 0.69 | PIK3CA (0.45) | KDRFGFR3PIK3CAMTOR | |
| SCHEMBL3383110 | 0.68 | RET (0.48) | KDRFGFR3 | |
| SCHEMBL3383912 | 0.67 | KDR (0.51) | KDRFGFR3RAF1 | |
| SCHEMBL3189872 | 0.66 | KDR (0.50) | KDRFGFR3RIPK2RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904494-B1 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS | LILLY CO ELI (US) | 2010-12-01 | — | — | EP | disclosed |