⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2942968 | 0.93 | SIGMAR1 (0.35) | — | |
| SCHEMBL10813588 | 0.86 | KEAP1 (0.34) | — | |
| SCHEMBL1685344 | 0.79 | — | — | |
| SCHEMBL7072086 | 0.79 | — | — | |
| SCHEMBL5174927 | 0.77 | GNAI3 (0.35) | — | |
| Bromide SCHEMBL1920320 | 0.77 | — | — | |
| SCHEMBL11407357 | 0.77 | HRH3 (0.32) | — | |
| SCHEMBL19599281 | 0.74 | — | — | |
| SCHEMBL4992871 | 0.73 | — | — | |
| SCHEMBL1193464 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1506176-B1 | AMINOINDAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM | PFIZER ITALIA SRL (IT) | 2013-04-24 | — | — | EP | claimed |
| WO-2012148550-A1 | PRODRUGS OF THERAPEUTIC COMPOUNDS | MYREXIS, INC. (US) | 2012-11-01 | — | — | WO | disclosed |
| EP-0976815-B1 | Lubricating composition with improved bearing corrosion protection | LUBRIZOL CORP (US) | 2010-12-01 | — | — | EP | disclosed |
| EP-0972819-B1 | Lubricating compositions | LUBRIZOL CORP (US) | 2008-04-09 | — | — | EP | disclosed |
| EP-0976814-B1 | Lubricating compositions with reduced bearing corrosion | LUBRIZOL CORP (US) | 2004-03-17 | — | — | EP | disclosed |
| US-6207624-B1 | Engine oil having dispersant and aldehyde/epoxide for improved seal performance, sludge and deposit performance | THE LUBRIZOL CORPORATION | 2001-03-27 | — | — | US | disclosed |
| WO-2001011062-A2 | POLYAMINE ACCUMULATION IN PLANTS | JOHN INNES CENTRE (GB) | 2001-02-15 | — | — | WO | disclosed |
| EP-0976814-A1 | Lubricating compositions with reduced bearing corrosion | The Lubrizol Corporation (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0976815-A2 | Lubricating composition with improved bearing corrosion protection | The Lubrizol Corporation (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0972819-A1 | Lubricating compositions | The Lubrizol Corporation (US) | 2000-01-19 | — | — | EP | disclosed |
| US-6010986-A | Alcohol borate esters to improve bearing corrosion in engine oils | THE LUBRIZOL CORPORATION (US) | 2000-01-04 | — | — | US | disclosed |
| US-6008165-A | Alcohol borate esters and borated dispersants to improve bearing corrosion in engine oils | THE LUBRIZOL CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| US-4454059-A | REACTING PHENOLIC COMPOUND AND ALDEHYDE, THEN NEUTRALIZING WITH AMINE | THE LUBRIZOL CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |