Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.88 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.88 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.88 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.88 |
| ▸ | USP2 | O75604 | 1/20 | 0.88 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.88 |
| ▸ | BCHE | P06276 | 1/20 | 0.88 |
| ▸ | CFTR | P13569 | 1/20 | 0.88 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.88 |
| ▸ | ACHE | P22303 | 1/20 | 0.88 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.88 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.88 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.88 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5511965 | 0.98 | MEN1 (0.97) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL29618881 | 0.98 | MEN1 (0.97) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| Deoxyvasicinone SCHEMBL864139 | 0.94 | ALDH1A1 (1.00) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| Deoxyvasicinone SCHEMBL29359475 | 0.94 | ALDH1A1 (1.00) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL6920760 | 0.85 | KMT2A (0.73) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL6921486 | 0.83 | KMT2A (0.70) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL6922809 | 0.82 | MEN1 (0.68) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL6920772 | 0.82 | MEN1 (0.68) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL9994900 | 0.82 | MEN1 (0.68) | MEN1KMT2AHDAC6ALDH1A1KDM4E | |
| SCHEMBL9387899 | 0.81 | MEN1 (0.68) | MEN1KMT2AHDAC6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272986-A | A compound for inhibiting acetylcholinesterase activity, and preparation method and uses thereof | XIAMEN MEDICAL COLLEGE | 2016-01-27 | — | — | CN | disclosed |
| US-8642660-B2 | Method for altering the lifespan of eukaryotic organisms | THE UNIVERSITY OF ROCHESTER (US) | 2014-02-04 | — | — | US | disclosed |
| US-20090163545-A1 | Method For Altering The Lifespan Of Eukaryotic Organisms | UNIVERSITY OF ROCHESTER (US) | 2009-06-25 | — | — | US | disclosed |
| WO-2005077393-A1 | HERBAL FORMULATION COMPRISING EXTRACTS OF ADHATODA, HEDYCHIUM AND CURCUMA AS COUGH SYRUP | RANBAXY LABORATORIES LIMITED (IN) | 2005-08-25 | — | — | WO | disclosed |
| US-4588526-A | Bronchodilatory azepino(1,2-A)pyrimidine derivatives and acid addition salts thereof and bronchodilating pharmaceutical compositions containing same | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT (HU) | 1986-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163545-A1 | Method For Altering The Lifespan Of Eukaryotic Organisms | TUFM, MRM1, HOGA1 | MEN1 2524/4885KMT2A 2277/4885HDAC6 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.