Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 6/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | MTOR | P42345 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 5/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.32 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | MERTK | Q12866 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5492557 | 0.88 | FEN1 (0.31) | FEN1 | |
| SCHEMBL29975352 | 0.78 | PIK3CA (0.34) | PIK3CA | |
| SCHEMBL2634024 | 0.74 | DHFR (0.42) | DHFRDCPS | |
| SCHEMBL12466143 | 0.74 | KDM1A (0.40) | MAPK1DHFRDCPSFEN1BACE1 | |
| SCHEMBL481935 | 0.72 | CYP11B2 (0.40) | MAPK1PIK3CAAKT1MTORDHFR | |
| Hydrochloric Acid SCHEMBL28266713 | 0.72 | HRH3 (0.46) | PIK3CAMTORPIK3CDPIK3CBPIK3CG | |
| SCHEMBL21848173 | 0.71 | MAPK1 (0.38) | MAPK1PIK3CAMTORDHFRMAP3K12 | |
| SCHEMBL1564767 | 0.71 | MAPK1 (0.38) | MAPK1DHFRDCPSCSF1RFEN1 | |
| Ammonia Solution, Strong SCHEMBL16914060 | 0.70 | HTT (0.46) | CSF1R | |
| SCHEMBL25924998 | 0.69 | PDE1A (0.34) | MAPK1MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056524-A1 | Compound | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056524-A1 | Compound | NR3C2, NR3C1, NR2E3 | MAPK1 652/4885PIK3CA 1362/4885AKT1 778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.