SCHEMBL338635

SCHEMBL338635

NCCCCC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LNPEP Q9UIQ6 3/20 0.66
ERAP2 Q6P179 2/20 0.66
SLC7A5 Q01650 1/20 0.54
YARS1 P54577 2/20 0.52
NPY1R P25929 1/20 0.52
NPY2R P49146 1/20 0.52
NPY4R P50391 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.49
ENPEP Q07075 2/20 0.48
NPPA P01160 1/20 0.48
MME P08473 1/20 0.48
ACE P12821 1/20 0.48
ECE1 P42892 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29370934 1.00 LNPEP (0.66) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL29386049 1.00 LNPEP (0.66) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL29371447 1.00 LNPEP (0.66) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL338636 1.00 LNPEP (0.66) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL29405990 0.99 LNPEP (0.65) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL30090915 0.97 LNPEP (0.64) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL30523264 0.96 LNPEP (0.63) LNPEPERAP2SLC7A5NPY1RNPY2R
SCHEMBL29406227 0.96 LNPEP (0.61) LNPEPERAP2SLC7A5YARS1NPY1R
SCHEMBL30931517 0.95 LNPEP (0.62) LNPEPERAP2NPY1RNPY2RNPY4R
SCHEMBL30118045 0.95 LNPEP (0.62) LNPEPERAP2NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 140 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11040108-B2 Amino acid- and peptide-steroid conjugates and use thereof BRANDEIS UNIVERSITY (US) 2021-06-22 US claimed
US-7052872-B1 Bi-specific antibodies for pre-targeting diagnosis and therapy IMMUNOMEDICS, INC. (US) 2006-05-30 US claimed
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-04-20 US disclosed
EP-4074694-A1 AMINO ACID-, PEPTIDE- AN POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AN USES THEREOF Massachusetts Institute Of Technology (US) 2022-10-19 EP disclosed
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-10-22 US disclosed
US-20200197389-A1 METHODS FOR DETECTING DYSBIOSIS AND TREATING SUBJECTS WITH DYSBIOSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2020-06-25 US disclosed
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof MASSACHUSETTS INTSTITUTE OF TECHNOLOGY (US) 2020-06-16 US disclosed
EP-3634405-A1 METHODS FOR DETECTING DYSBIOSIS AND TREATING SUBJECTS WITH DYSBIOSIS The Regents of The University of California (US) 2020-04-15 EP disclosed
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2019-03-14 US disclosed
WO-2018209307-A1 METHODS FOR DETECTING DYSBIOSIS AND TREATING SUBJECTS WITH DYSBIOSIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-11-15 WO disclosed
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2018-02-08 US disclosed
EP-0522004-B1 USE OF COPPER(II) CONTAINING COMPOUNDS TO ACCELERATE WOUND HEALING PROCYTE CORP (US) 1999-12-15 EP disclosed
WO-1999010016-A1 COMBINATORIAL LIBRARY RESOLUTION PHARMACEUTICALS INC. (CA) 1999-03-04 WO disclosed
EP-0419387-B1 Hydrophilic derivatives, diagnostic and therapeutic applications, kits and immunological reagents IMMUNOTECH PARTNERS (FR) 1996-11-20 EP disclosed
US-H1312-H Method for the preparation of gyk-dtpa CYTOGEN CORPORATION (US) 1994-05-03 US disclosed
US-5274076-A N-alpha-acetyl,N-epsilon(histamine-succinyl-glycl)-L-lysyl-L -tyrosyl-N-epsilon(histamine-succinyl-glycyl)-L-lysylamide IMMUNOTECH PARTNERS (FR) 1993-12-28 US disclosed
EP-0522004-A1 USE OF COPPER(II) CONTAINING COMPOUNDS TO ACCELERATE WOUND HEALING PROCYTE CORPORATION (US) 1993-01-13 EP disclosed
US-5164367-A Complexes with peptides PROCYTE CORPORATION (US) 1992-11-17 US disclosed
WO-1991014437-A2 USE OF COPPER(II) CONTAINING COMPOUNDS TO ACCELERATE WOUND HEALING PROCYTE CORPORATION (US) 1991-10-03 WO disclosed
EP-0419387-A1 Hydrophilic derivatives, diagnostic and therapeutic applications, kits and immunological reagents IMMUNOTECH PARTNERS: Société en Commandite par Actions dite (FR) 1991-03-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200330501-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 LNPEP 11/4885ERAP2 535/4885SLC7A5 20/4885
US-11040108-B2 Amino acid- and peptide-steroid conjugates and use thereof NGLY1, CD81, MTX1 LNPEP 41/4885ERAP2 1144/4885SLC7A5 145/4885
US-20230124955-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 LNPEP 11/4885ERAP2 535/4885SLC7A5 20/4885
US-20190076462-A1 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 LNPEP 11/4885ERAP2 535/4885SLC7A5 20/4885
US-20180036333-A9 AMINO ACID-, PEPTIDE- AND POLYPEPTIDE-LIPIDS, ISOMERS, COMPOSITIONS, AND USES THEREOF APLNR, NPPA, ARGLU1 LNPEP 11/4885ERAP2 535/4885SLC7A5 20/4885
US-10682374-B2 Amino acid-, peptide- and polypeptide-lipids, isomers, compositions, and uses thereof APLNR, NPPA, ARGLU1 LNPEP 11/4885ERAP2 535/4885SLC7A5 20/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.