Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | UBE2N | P61088 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3650252 | 0.73 | HTT (0.35) | SPHK1HTT | |
| SCHEMBL11213426 | 0.70 | SPHK2 (0.35) | SPHK1CETPSPHK2 | |
| SCHEMBL2454531 | 0.70 | ALDH1A1 (0.36) | SPHK1CYP2D6CETPHTTGMNN | |
| SCHEMBL25856486 | 0.70 | SPHK1 (0.41) | SPHK1CYP2D6CETPHTTGMNN | |
| SCHEMBL3650242 | 0.69 | LMNA (0.38) | SPHK1CYP2D6CETPHTTGMNN | |
| SCHEMBL19092286 | 0.68 | SPHK2 (0.33) | SPHK1CETPSPHK2 | |
| SCHEMBL7778192 | 0.67 | CA12 (0.33) | LMNA | |
| SCHEMBL7776738 | 0.67 | FDPS (0.35) | LMNA | |
| SCHEMBL30353887 | 0.67 | TDP1 (0.35) | LMNA | |
| SCHEMBL5435143 | 0.66 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137504-A1 | RADICAL COLD CURING OF SYNTHETIC RESINS BASED ON MODIFIED POLY(METH)ACRYLATES COMPRISING REACTIVE ETHYLENIC GROUPS | ASHLAND-SUEDCHEMIE-KERNFEST GMBH (DE) | 2010-06-03 | — | — | US | disclosed |