SCHEMBL338678

SCHEMBL338678

Cc1cc(C)c(C(=O)[PH](=O)OCC(c2ccccc2)c2ccccc2)c(C)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.40
SLC6A2 P23975 2/20 0.39
SLC6A4 P31645 2/20 0.39
SLC6A3 Q01959 2/20 0.39
MEN1 O00255 3/20 0.37
KMT2A Q03164 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ALDH1A1 P00352 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.36
CACNA1G O43497 1/20 0.36
CACNA2D1 P54289 1/20 0.36
CACNA1B Q00975 1/20 0.36
CACNB1 Q02641 1/20 0.36
CACNA1C Q13936 1/20 0.36
TACR1 P25103 5/20 0.36
PPARA Q07869 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL225077 0.78 GAA (0.41) MEN1KMT2AL3MBTL1SMN1; SMN2ATM
SCHEMBL3109009 0.76 TACR1 (0.39) SLC6A2SLC6A4SLC6A3MEN1KMT2A
SCHEMBL7086681 0.76 NPC1 (0.42) MEN1KMT2ASMN1; SMN2ATMTDP1
SCHEMBL6374832 0.76 SMN1; SMN2 (0.38) MEN1KMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL28401917 0.75 LMNA (0.38) BRD4SLC6A2SLC6A4SLC6A3MEN1
SCHEMBL8171301 0.75 LMNA (0.35) MEN1KMT2AHPGD
SCHEMBL6204059 0.74 BRD4 (0.50) BRD4SLC6A2SLC6A4SLC6A3MEN1
SCHEMBL22612081 0.74 LMNA (0.34) MEN1KMT2AHPGD
Lithium SCHEMBL29406710 0.74 LMNA (0.34) MEN1KMT2AHPGD
SCHEMBL7183325 0.71 CYP2C9 (0.38) MEN1KMT2AALDH1A1TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110382561-B Sealing composition 味之素株式会社 2023-01-31 CN disclosed
US-11370942-B2 Pressure-sensitive adhesive composition LG CHEM, LTD. (KR) 2022-06-28 US disclosed
CN-111757910-B Sealing resin composition 味之素株式会社 2022-06-24 CN disclosed
CN-111757910-A Sealing resin composition 味之素株式会社 2020-10-09 CN disclosed
US-10761443-B2 Charge transport molecule having hydrogen for an overcoat of a photoconductor LEXMARK INTERNATIONAL, INC. (US) 2020-09-01 US disclosed
US-10732528-B2 Overcoat for a photoconductor with tetrafunctional radical polymerizable charge transport molecule having hydrogen LEXMARK INTERNATIONAL, INC. (US) 2020-08-04 US disclosed
US-10684565-B2 Photoconductor overcoat having a charge transport molecule with four radical polymerizable hydrophilic functional groups containing an oxygen atom and method of making the same LEXMARK INTERNATIONAL, INC. (US) 2020-06-16 US disclosed
US-10481512-B2 Photoconductor having protective overcoat layer with a charge transport molecule with four radical polymerizable hydrophilic functional groups containing an oxygen atom and method of making the same LEXMARK INTERNATIONAL, INC. (US) 2019-11-19 US disclosed
US-10435596-B2 Pressure-sensitive adhesive composition LG CHEM, LTD. (KR) 2019-10-08 US disclosed
US-20190271923-A1 OVERCOAT FOR A PHOTOCONDUCTOR WITH TETRAFUNCTIONAL RADICAL POLYMERIZABLE CHARGE TRANSPORT MOLECULE HAVING HYDROGEN LEXMARK INTERNATIONAL, INC. 2019-09-05 US disclosed
US-20060051689-A1 Image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2006-03-09 US disclosed
US-20060014096-A1 Image forming method, image forming apparatus and process cartridge therefor RICOH COMPANY, LTD. (JP) 2006-01-19 US disclosed
US-20050266325-A1 Outer layer is the crosslinked product of a urethane oligomer having radical polymerizing functional group (e.g., from di(meth)acrylated 1,2,9,10-tetrahydroxy-4,7-dioxadecane), a crosslinking agent, and a reactive charge transport agent, especially acrylated di- or triarylamine; performance & reliability RICOH COMPANY, LTD. (JP) 2005-12-01 US disclosed
US-20050266328-A1 Electrophotographic photoreceptor, and image forming method, apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY LIMITED (JP) 2005-12-01 US disclosed
EP-1600822-A2 Electrophotographic photoreceptor and image forming method, apparatus and process cartridge therefor using the photoreceptor Ricoh Company, Ltd. (JP) 2005-11-30 EP disclosed
US-20050141919-A1 Image forming apparatus and image forming method RICOH COMPANY, LTD. (JP) 2005-06-30 US disclosed
US-6855746-B2 Process for the production of molded particles for enzyme- or microbial cell-immobilization KANSAI PAINT CO., LTD. (JP) 2005-02-15 US disclosed
US-6706778-B2 AQUEOUS LIQUID CONTAINING POLYURETHANE IS SUBJECTED TO GELATION, THEN SUBJECTED TO PHOTOPOLYMERIZATION AND/OR THERMOPOLYMERIZATION TO TO CAUSE CROSSLINKING REACTION OF ETHYLENICALLY UNSATURATED GROUP IN PARTICULATE GEL KANSAI PAINT CO., LTD. (JP) 2004-03-16 US disclosed
US-20030100636-A1 Process for the production of molded particles for enzyme- or microbial cell-immobilization KANSAI PAINT CO., LTD. (JP) 2003-05-29 US disclosed
US-20020143104-A1 Process for the production of molded particles for microbial cell-immobilization KANSAI PAINT CO., LTD. (JP) 2002-10-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190271923-A1 OVERCOAT FOR A PHOTOCONDUCTOR WITH TETRAFUNCTIONAL RADICAL POLYMERIZABLE CHARGE TRANSPORT MOLECULE HAVING HYDROGEN SLC43A1, DRD4, SLC7A5 BRD4 2145/4885SLC6A2 492/4885SLC6A4 13/4885
US-10761443-B2 Charge transport molecule having hydrogen for an overcoat of a photoconductor SLC43A1, SLC46A1, SLC3A2 BRD4 1770/4885SLC6A2 154/4885SLC6A4 23/4885
US-10732528-B2 Overcoat for a photoconductor with tetrafunctional radical polymerizable charge transport molecule having hydrogen SLC43A1, DRD4, SLC7A5 BRD4 2145/4885SLC6A2 492/4885SLC6A4 13/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.