Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3388376 | 0.85 | PNMT (0.35) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7945483 | 0.80 | PNMT (0.32) | PNMTNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL5351419 | 0.79 | PNMT (0.44) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL7945298 | 0.76 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL218803 | 0.76 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Fluoride Ion SCHEMBL1130432 | 0.76 | PNMT (0.44) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL4455496 | 0.76 | — | — | |
| SCHEMBL2268057 | 0.74 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Fluoride Ion SCHEMBL1131088 | 0.74 | PNMT (0.35) | PNMTDRD2DRD4DRD3NPC1 | |
| Hydrochloric Acid SCHEMBL7934594 | 0.74 | PNMT (0.31) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829495-B2 | Olefin polymerization process with alkyl-substituted metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-20050032992-A1 | Olefin polymerization process with alkyl-substituted metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. | 2005-02-10 | — | — | US | disclosed |
| US-6759499-B1 | POLYMER PRODUCTS HAVING NARROW COMPOSITION DISTRIBUTIONS, LOW MELT INDEX RATIOS, AND, OPTIONALLY, HIGH MELT STRENGTH | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-06 | — | — | US | disclosed |
| US-6489413-B1 | AN OLEFIN POLYMERIZATION PROCESS COMPRISING CONTACTING ETHYLENE, ALONE OR WITH ONE OR MORE OLEFINICALLY UNSATURATED COMONOMERS, UNDER SUITABLE POLYMERIZATION CONDITIONS WITH A GROUP 3-6 METALLOCENE CATALYST COMPOUND CONTAINING TWO | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-12-03 | — | — | US | disclosed |