Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride Ion SCHEMBL1131013 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL3386797 | 0.76 | PNMT (0.34) | — | |
| Hydrochloric Acid SCHEMBL28371794 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL536233 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL2804146 | 0.67 | — | — | |
| Fluoride Ion SCHEMBL27619097 | 0.67 | — | — | |
| SCHEMBL6303309 | 0.66 | — | — | |
| SCHEMBL6250606 | 0.66 | — | — | |
| SCHEMBL4811799 | 0.66 | — | — | |
| SCHEMBL6053802 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6281320-B1 | POLYOLEFIN CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-08-28 | — | — | US | claimed |
| US-20090131705-A1 | Practical, Cost-Effective Synthesis of Ubiquinones | ZYMES, LLC | 2009-05-21 | — | — | US | disclosed |
| US-20080086013-A1 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHESIS OF UNIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-04-10 | — | — | US | disclosed |
| WO-2008019196-A2 | CARBOMETALLATION OF ALKYNES AND IMPROVED SYNTHSIS OF UBIQUINONES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-02-14 | — | — | WO | disclosed |
| US-20060167289-A1 | Practical, cost-effective synthesis of ubiquinones | ZYMES, LLC (US) | 2006-07-27 | — | — | US | disclosed |
| EP-1226191-B1 | CATALYST SYSTEMS AND THEIR USE IN A POLYMERIZATION PROCESS | UNIVATION TECH LLC (US) | 2005-07-20 | — | — | EP | disclosed |
| US-6620757-B2 | As polymerization catalyst in polymerizing olefin(s) | UNIVATION TECHNOLOGIES, LLC | 2003-09-16 | — | — | US | disclosed |
| US-20020082367-A1 | Catalyst systems and their use in a polymerization process | MCCONVILLE DAVID H (US) | 2002-06-27 | — | — | US | disclosed |
| US-6380328-B1 | COORDINATION CATALYSTS | UNIVATION TECHNOLOGIES, LLC | 2002-04-30 | — | — | US | disclosed |
| US-6281320-B1 | POLYOLEFIN CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-08-28 | — | — | US | disclosed |