SCHEMBL338687

SCHEMBL338687

CCP(=O)(O)C(C)C(C)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.35
LAP3 P28838 1/20 0.35
RNPEP Q9H4A4 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP3 P08254 1/20 0.33
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL339954 0.83 ANPEP (0.33) ANPEPLAP3
SCHEMBL18096847 0.82 ANPEP (0.35) ANPEPLAP3MMP1MMP2MMP3
SCHEMBL339854 0.80 LAP3 (0.42) ANPEPLAP3RNPEPMMP1
SCHEMBL338997 0.79 TRPM8 (0.39)
SCHEMBL2988978 0.79 RNPEP (0.34) RNPEPMMP1MMP2MMP3TP53
SCHEMBL339956 0.78 PPARD (0.33) ANPEPLAP3RNPEP
SCHEMBL339910 0.78 LPAR3 (0.45)
SCHEMBL339477 0.77 LPAR3 (0.48)
SCHEMBL1313336 0.76 ANPEP (0.37) ANPEPLAP3MMP1MMP2MMP3
SCHEMBL2984813 0.75 TP53 (0.38) RNPEPMMP1MMP2TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1832594-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2011-05-18 EP claimed
EP-1832595-B1 Compounds of mono-carboxyl functionalised dialkylphosphine acid salts and other components, a method for their manufacture and their application CLARIANT FINANCE BVI LTD (VG) 2009-07-15 EP claimed
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US claimed
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US claimed
US-8097753-B2 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT FINANCE (BVI) LIMITED (VG) 2012-01-17 US disclosed
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US disclosed
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation CLARIANT INTERNATIONAL LTD 2007-09-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213563-A1 Mixtures composed of monocarboxy-functionalized dialkylphosphinic acid salts, their use und a process for their preparation DBH, HBB, ALKBH3 ANPEP 3632/4885LAP3 4306/4885RNPEP 2511/4885
US-20070213436-A1 Mixtures composed or monocarboxy-functionalized dialkylphosphinic acids, their use and a process for their preparation PAH, ALKBH3, FTO ANPEP 1542/4885LAP3 2642/4885RNPEP 945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.