SCHEMBL3386873

SCHEMBL3386873

Cc1ccc(S(=O)(=O)O)cc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 1/20 0.50
FLT4 P35916 1/20 0.50
KDR P35968 1/20 0.50
ALDH1A1 P00352 4/20 0.49
MAPT P10636 2/20 0.49
CASP6 P55212 1/20 0.49
KMT2A Q03164 1/20 0.49
CA2 P00918 1/20 0.49
PTGS2 P35354 2/20 0.46
PTGS1 P23219 1/20 0.45
CYP3A4 P08684 1/20 0.45
HSD17B10 Q99714 1/20 0.44
SNCA P37840 1/20 0.43
LMNA P02545 2/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
PKM P14618 2/20 0.42
THRB P10828 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TSHR P16473 1/20 0.41
NT5E P21589 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31531993 1.00 FLT1 (0.50) FLT1FLT4KDRALDH1A1MAPT
SCHEMBL13277970 0.98 FLT1 (0.49) FLT1FLT4KDRALDH1A1MAPT
SCHEMBL8887429 0.98 FLT1 (0.49) FLT1FLT4KDRALDH1A1MAPT
Hydrochloric Acid SCHEMBL3866369 0.98 FLT1 (0.49) FLT1FLT4KDRALDH1A1MAPT
SCHEMBL4208852 0.85 LMNA (0.48) ALDH1A1MAPTCASP6KMT2ACA2
SCHEMBL5936707 0.84 LMNA (0.50) FLT1FLT4KDRALDH1A1MAPT
SCHEMBL27901125 0.83 HSD17B10 (0.47) ALDH1A1MAPTCA2HSD17B10LMNA
SCHEMBL13278275 0.83 LMNA (0.47) ALDH1A1MAPTCASP6KMT2ACA2
Hydrochloric Acid SCHEMBL28076325 0.83 LMNA (0.47) ALDH1A1MAPTCASP6KMT2ACA2
SCHEMBL242381 0.83 FLT1 (0.46) FLT1FLT4KDRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 384 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115414882-B System and process for continuously preparing 4-methyl-5-chlorobenzenesulfonic acid 浙江工业大学 2025-03-18 CN claimed
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-03-13 US claimed
WO-2025029842-A2 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY- PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-L-YL]PIPERIDINE-L-CARBONYL]-4- METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-L-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF PRINCIPIA BIOPHARMA INC. (US) 2025-02-06 WO claimed
CN-115414882-A System and process for continuously preparing 4-methyl-5-chlorobenzene sulfonic acid 浙江工业大学 2022-12-02 CN claimed
CN-111183214-B Leuco colorants as bluing agents in laundry care compositions 宝洁公司 2022-06-14 CN claimed
US-11299634-B2 Reactive leuco compounds and compositions comprising the same MILLIKEN & COMPANY (US) 2022-04-12 US claimed
US-20220089974-A1 LAUNDRY CARE COMPOSITIONS AND METHODS FOR DETERMINING THEIR AGE PROCTER & GAMBLE (US) 2022-03-24 US claimed
CN-111183215-B Laundry care compositions and methods for determining their age 宝洁公司 2022-03-15 CN claimed
US-11230686-B2 Laundry care compositions and methods for determining their age THE PROCTER & GAMBLE COMPANY (US) 2022-01-25 US claimed
CN-111194348-B Leuco colorants in combination with secondary brighteners as bluing agents in laundry care compositions 宝洁公司 2021-12-03 CN claimed
US-20180119068-A1 METHODS OF USING LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2018-05-03 US claimed
CN-105541667-B The method that continuous conduit metaplasia produces CLT acid itrated compound 浙江秦燕科技股份有限公司 2018-04-20 CN claimed
EP-0434739-B1 PROCESS FOR THE PREPARATION OF 4-SULFO-2-CHLOROBENZOIC ACID SOLVAY INTEROX LTD (GB) 1995-03-29 EP claimed
US-5139628-A Selectively brominating 2-chloro-4-toluenesulfonic acid in anhydrous solvent with bromine dissociated by radiation, extracting into aqueous phase, hydrolyzing, oxidizing with percarboxylic acid or bromine INTEROX CHEMICALS LIMITED (GB) 1992-08-18 US claimed
EP-0434739-A1 PROCESS FOR THE PREPARATION OF 4-SULFO-2-CHLOROBENZOIC ACID. INTEROX CHEMICALS LTD (GB) 1991-07-03 EP claimed
WO-1990005717-A1 PREPARATION OF 2-CHLORO-4-TOLUENESULFONIC ACID ICI AMERICAS INC. (US) 1990-05-31 WO claimed
WO-1990002731-A1 PROCESS FOR THE PREPARATION OF 4-SULFO-2-CHLOROBENZOIC ACID INTEROX CHEMICALS LIMITED (GB) 1990-03-22 WO claimed
US-4267319-A CATIONIC DYES AND N-HETEROCYCLIC CATIONIC POLYMERS; PRINTING PAPER; ORANGE OR RED BASF AKTIENGESELLSCHAFT (DE) 1981-05-12 US claimed
US-4171459-A Manufacture of α-naphthol BASF AKTIENGESELLSCHAFT (DE) 1979-10-16 US claimed
US-4131619-A Preparation of 2-chloro-4-toluenesulfonyl chloride THE DOW CHEMICAL COMPANY (US) 1978-12-26 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084085-A1 PROCESS OF MAKING 2-[(3R)-2-[4-AMINO-3-(2-FLUORO-4-PHENOXY-PHENYL)PYRAZOLO[3,4-D]PYRIMIDIN-1-YL]PIPERIDINE-1-CARBONYL]-4-METHYL-4[4-(OXETAN-3-YL)PIPERAZIN-1-YL]-PENT-2-ENENITRILE AND SOLVATE FORMS THEREOF EPB41, HTR4, HTR3C FLT1 1348/4885FLT4 177/4885KDR 917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.