Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 known ✓ | P20309 | 15/20 | 0.88 |
| ▸ | CHRM2 known ✓ | P08172 | 4/20 | 0.88 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.88 |
| ▸ | CHRM5 known ✓ | P08912 | 1/20 | 0.88 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.88 |
| ▸ | HRH1 | P35367 | 1/20 | 0.88 |
| ▸ | HTR2B | P41595 | 1/20 | 0.88 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.88 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1222146 | 0.99 | CHRM3 (0.88) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12884377 | 0.97 | CHRM3 (0.86) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL4106576 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL131054 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL417981 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL417980 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL132614 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL41436 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL1900235 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 | |
| Glycopyrronium SCHEMBL2335685 | 0.94 | CHRM3 (1.00) | CHRM3CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4011353-A1 | NEW COSMETICS SOLVENTS COMPRISING ASCORBIC ACID | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | claimed |
| EP-4011354-A1 | NEW COSMETICS SOLVENTS BASED ON TWO DIFFERENT COMPONENTS | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | claimed |
| EP-4011352-A1 | NEW COSMETICS SOLVENTS BASED ON THREE DIFFERENT COMPONENTS | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | claimed |
| CN-108601714-B | Antiperspirant stick in O/W emulsion form | 拜尔斯道夫股份有限公司 | 2021-10-22 | — | — | CN | claimed |
| EP-3432855-B1 | ANTIPERSPIRANT STICK IN THE FORM OF AN O/W EMULSION | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | claimed |
| EP-4011353-A1 | NEW COSMETICS SOLVENTS COMPRISING ASCORBIC ACID | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | disclosed |
| EP-4011352-A1 | NEW COSMETICS SOLVENTS BASED ON THREE DIFFERENT COMPONENTS | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | disclosed |
| EP-4011354-A1 | NEW COSMETICS SOLVENTS BASED ON TWO DIFFERENT COMPONENTS | Beiersdorf AG (DE) | 2022-06-15 | — | — | EP | disclosed |
| CN-108601714-B | Antiperspirant stick in O/W emulsion form | 拜尔斯道夫股份有限公司 | 2021-10-22 | — | — | CN | disclosed |
| EP-3432855-B1 | ANTIPERSPIRANT STICK IN THE FORM OF AN O/W EMULSION | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| EP-2969027-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND FRAGRANCES | BEIERSDORF AG (DE) | 2020-10-14 | — | — | EP | disclosed |
| US-20190105240-A1 | ANTIPERSPIRANT STICK IN THE FORM OF AN O/W EMULSION | BEIERSDORF AG (DE) | 2019-04-11 | — | — | US | disclosed |
| EP-2968100-B1 | COMBINATION OF ALKYLAMIDOTHIAZOLES AND PRESERVATIVES | BEIERSDORF AG (DE) | 2019-04-10 | — | — | EP | disclosed |
| EP-2969028-B1 | COMPOSITIONS OF ALKYLAMIDOTHIAZOLES AND UV FILTER SUBSTANCES | BEIERSDORF AG (DE) | 2018-05-09 | — | — | EP | disclosed |
| EP-2758383-B1 | AROMATIC AMIDOTHIAZOLES, COSMETIC AND DERMATOLOGICAL PREPARATIONS CONTAINING THEM, AND THEIR USE FOR THE TREATMENT AND PROPHYLAXIS OF UNWANTED PIGMENTATION OF THE SKIN | BEIERSDORF AG (DE) | 2016-11-09 | — | — | EP | disclosed |
| WO-2010046012-A2 | WATER-FREE ANTIPERSPIRANT STICKS COMPRISING MICROCRYSTALLINE WAX | BEIERSDORF AG (DE) | 2010-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190105240-A1 | ANTIPERSPIRANT STICK IN THE FORM OF AN O/W EMULSION | CUTA, ADH1A, DGAT1 | CHRM3 405/4885CHRM2 353/4885CHRM4 816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.