Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725082 | 0.99 | MTNR1A (0.33) | MTNR1AMTNR1BSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL1710762 | 0.88 | SMN1; SMN2 (0.34) | MTNR1AMTNR1BALDH1A1MAPK1TDP1 | |
| SCHEMBL1724736 | 0.87 | MTNR1A (0.40) | MTNR1AMTNR1BSLC6A2SLC6A4ALDH1A1 | |
| SCHEMBL1710722 | 0.86 | SMN1; SMN2 (0.35) | MTNR1AMTNR1BALDH1A1MAPK1TDP1 | |
| SCHEMBL1726496 | 0.83 | CYP3A4 (0.35) | ALDH1A1MAPK1TDP1CNR2LMNA | |
| SCHEMBL1725320 | 0.82 | MALT1 (0.36) | ALDH1A1MAPK1TDP1CNR2LMNA | |
| SCHEMBL13400259 | 0.81 | HDAC6 (0.38) | MTNR1AMTNR1B | |
| SCHEMBL13400239 | 0.81 | HDAC6 (0.38) | MTNR1AMTNR1B | |
| SCHEMBL1722655 | 0.81 | ALDH1A1 (0.33) | SLC6A2SLC6A4ALDH1A1MAPK1TDP1 | |
| SCHEMBL614292 | 0.80 | MAPK14 (0.36) | MTNR1AMTNR1BMAPK1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | MTNR1A 109/4885MTNR1B 82/4885SLC6A2 2267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.