SCHEMBL338764

SCHEMBL338764

O=C1CCC(OC(=O)O)=NN1

nearest known ligand 0.39

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
MAPT P10636 4/20 0.35
ALDH1A1 P00352 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.33
RAB9A P51151 3/20 0.32
NPC1 O15118 2/20 0.32
PDE4A P27815 1/20 0.32
PDE4B Q07343 1/20 0.32
PDE4C Q08493 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
LMNA P02545 2/20 0.31
KDM4E B2RXH2 1/20 0.31
SMYD3 Q9H7B4 1/20 0.31
NPY1R P25929 1/20 0.30
NPY2R P49146 1/20 0.30
RXFP1 Q9HBX9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10762089 0.79 RAB9A (0.38) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL13279155 0.75
SCHEMBL337724 0.68 NPC1 (0.44) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL27040200 0.64 SMN1; SMN2 (0.39) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL5201218 0.63 SMYD3 (0.44) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL13938473 0.63 NPC1 (0.46) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL5679231 0.62 RAB9A (0.39) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A
SCHEMBL5679235 0.62 ALDH1A1 (0.41) SMN1; SMN2MAPTALDH1A1L3MBTL1LMNA
SCHEMBL1092516 0.61
SCHEMBL10045647 0.60 LMNA (0.44) SMN1; SMN2MAPTALDH1A1L3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8535430-B2 Hydrazine filtration method and system NEW MEXICO HIGHLANDS UNIVERSITY (US) 2013-09-17 US disclosed
US-8097074-B2 Air filtration and absorption method and system for the remediation of hydrazine NEW MEXICO HIGHLANDS UNIVERSITY (US) 2012-01-17 US disclosed
US-20110194988-A1 HYDRAZINE SPILL PAD APPARATUS AND METHOD OF MANUFACTURING NEW MEXICO HIGHLANDS UNIVERSITY 2011-08-11 US disclosed
US-20110182780-A1 HYDRAZINE FILTRATION METHOD AND SYSTEM NEW MEXICO HIGHLANDS UNIVERSITY 2011-07-28 US disclosed
US-20110011266-A1 AIR FILTRATION AND ABSORPTION METHOD AND SYSTEM FOR THE REMEDIATION OF HYDRAZINE NEW MEXICO HIGHLANDS UNIVERSITY 2011-01-20 US disclosed
US-20110010878-A1 HYDRAZINE DECONTAMINATION WIPES NEW MEXICO HIGHLANDS UNIVERSITY 2011-01-20 US disclosed
US-7074959-B2 Methods and systems for remediating hydrazine-contaminated equipment and/or surfaces NEW MEXICO HIGHLANDS UNIVERSITY (US) 2006-07-11 US disclosed
US-20040024251-A1 Methods and systems for hydrazine remediation HELVENSTON MERRITT C (US) 2004-02-05 US disclosed