Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP8 | P22894 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | MMP16 | P51512 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 8/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.36 |
| ▸ | NOS1 | P29475 | 3/20 | 0.36 |
| ▸ | NOS2 | P35228 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | CXCR1 | P25024 | 3/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2114086 | 0.80 | PTGS2 (0.44) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL2204495 | 0.77 | PTGS2 (0.56) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL7475089 | 0.75 | MIF (0.42) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL30222272 | 0.74 | PTGS2 (0.46) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL5983552 | 0.74 | PTGS2 (0.46) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL5112475 | 0.74 | PTGS2 (0.46) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL7822153 | 0.73 | PTGS2 (0.44) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL1343676 | 0.71 | PTGS2 (0.50) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL18797642 | 0.71 | PTGS2 (0.50) | CXCL8MMP2MMP9MMP8MMP12 | |
| SCHEMBL28158526 | 0.70 | L3MBTL1 (0.56) | PTGS2PTGS1MAPTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054068-A2 | CYCLIC ADENOSINE MONOPHOSPHATES FOR REDUCING THE FORMATION OF ADHESIONS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2010-05-14 | — | — | WO | disclosed |