SCHEMBL3387885

SCHEMBL3387885

Cc1cccc2c1nc1c(=O)n(C)c(=O)nc-1n2C[C@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.45
▸ KMT2A Q03164 4/20 0.45
▸ KDM4E B2RXH2 4/20 0.45
▸ USP2 O75604 3/20 0.45
▸ CASP1 P29466 3/20 0.45
▸ CASP7 P55210 3/20 0.45
▸ HSD17B10 Q99714 3/20 0.45
▸ BRCA1 P38398 2/20 0.45
▸ RECQL P46063 2/20 0.45
▸ HAT1 O14929 2/20 0.45
▸ RBBP7 Q16576 2/20 0.45
▸ MAPT P10636 2/20 0.45
▸ HTT P42858 2/20 0.45
▸ ALDH1A1 P00352 2/20 0.45
▸ LMNA P02545 1/20 0.45
▸ HBB P68871 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22830404 0.85 GSR (0.52) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL22830405 0.81 MEN1 (0.68) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL10250552 0.74 KMT2A (0.51) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL10250398 0.74 MEN1 (0.53) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL10250554 0.72 KMT2A (0.46) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL11304574 0.70 GSR (0.45) MEN1KMT2AKDM4ECASP1CASP7
SCHEMBL30935958 0.70 MEN1 (0.67) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL31481986 0.69 MEN1 (0.66) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL30176237 0.69 MEN1 (0.68) MEN1KMT2AKDM4EUSP2CASP1
SCHEMBL21743935 0.67 MEN1 (0.63) MEN1KMT2AKDM4EUSP2CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1345491-B1 STORAGE SOLUTION CONTAINING PHOTOSENSITIZER FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS GAMBRO INC (US) 2006-04-05 — — EP claimed
EP-1404379-A2 VIRAL INACTIVATION PROCESS USING ANTIOXIDANT Gambro, Inc. (US) 2004-04-07 — — EP claimed
US-20030215784-A1 Method and apparatus for inactivation of biological contaminants using photosensitizers TERUMO BCT BIOTECHNOLOGIES, LLC 2003-11-20 — — US claimed
WO-2002096471-A2 VIRAL INACTIVATION PROCESS USING ANTIOXIDANT GAMBRO, INC. (US) 2002-12-05 — — WO claimed
EP-3934594-A1 ENERGY AUGMENTATION STRUCTURES, EMITTERS OR COLLECTORS, FOR USE IN NON-INVASIVE IN-SITU PHOTOBIOMODULATION Immunolight, Llc. (US) 2022-01-12 — — EP disclosed
WO-2010009106-A1 ADVANCED METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS BOURKE FREDERIC A JR (US) 2010-01-21 — — WO disclosed
EP-1345491-B1 STORAGE SOLUTION CONTAINING PHOTOSENSITIZER FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS GAMBRO INC (US) 2006-04-05 — — EP disclosed
US-20040023201-A9 A platelet/additive solution and treatment comprising bicarbonate, citrate and glucose GAMBRO, INC. 2004-02-05 — — US disclosed
US-20030186213-A1 Blood component storage solutions containing a photosensitizer for viral inactivation MCBURNEY LAURA (US) 2003-10-02 — — US disclosed
EP-1345491-A1 STORAGE SOLUTION CONTAINING PHOTOSENSITIZER FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS Gambro, Inc. (US) 2003-09-24 — — EP disclosed
US-6548241-B1 A fluid to be used in the decontamination treatment and inthe storage of blood or blood components containing a nutrient, 7,8-dimethyl-10-ribityl isoalloxazine, a buffer and an anticoagulant GAMBRO, INC. 2003-04-15 — — US disclosed
WO-2002043485-A1 STORAGE SOLUTION CONTAINING PHOTOSENSITIZER FOR INACTIVATION OF BIOLOGICAL CONTAMINANTS GAMBRO, INC. (US) 2002-06-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030186213-A1 Blood component storage solutions containing a photosensitizer for viral inactivation HBG1, HBG2, HBB MEN1 1975/4885KMT2A 3625/4885KDM4E 3877/4885
US-20030215784-A1 Method and apparatus for inactivation of biological contaminants using photosensitizers PROC, PLG, PLPBP MEN1 4813/4885KMT2A 3553/4885KDM4E 2962/4885
US-20040023201-A9 A platelet/additive solution and treatment comprising bicarbonate, citrate and glucose PFKP, PF4, PDGFRB MEN1 2094/4885KMT2A 4399/4885KDM4E 4569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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