Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.31 |
| ▸ | SLC6A19 | Q695T7 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387918 | 1.00 | GAA (0.34) | GAAALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL3390368 | 0.84 | CYSLTR2 (0.40) | GAAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL3390377 | 0.84 | CYSLTR2 (0.40) | GAAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL1710641 | 0.82 | ALDH1A1 (0.35) | GAAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL1710636 | 0.82 | ALDH1A1 (0.35) | GAAALDH1A1KDM4EMTNR1AMTNR1B | |
| SCHEMBL3387256 | 0.78 | NAMPT (0.34) | ALDH1A1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL3387246 | 0.78 | NAMPT (0.34) | ALDH1A1TAS1R3TAS1R1L3MBTL1 | |
| SCHEMBL3388480 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3388475 | 0.78 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3390932 | 0.78 | ALDH1A1 (0.40) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | GAA 456/4885ALDH1A1 314/4885TAS1R3 170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.