Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388480 | 1.00 | ALDH1A1 (0.33) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL13400302 | 0.85 | EPHX1 (0.34) | ALDH1A1 | |
| SCHEMBL3385937 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL3385943 | 0.79 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL3389935 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3389932 | 0.78 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL3387918 | 0.78 | GAA (0.34) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3387914 | 0.78 | GAA (0.34) | ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL3389437 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL3389431 | 0.77 | ALDH1A1 (0.30) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ACUCELA, INC. (US) | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093865-A1 | SULPHUR-LINKED COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | ALDH1A2, MPST, CLN6 | ALDH1A1 314/4885TAS1R3 170/4885TAS1R1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.