Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | FGF23 | Q9GZV9 | 1/20 | 0.43 |
| ▸ | FOS | P01100 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24768620 | 0.88 | NFE2L2 (0.56) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| SCHEMBL888505 | 0.88 | NFE2L2 (0.56) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| SCHEMBL8447454 | 0.88 | NFE2L2 (0.56) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| SCHEMBL29242178 | 0.77 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| SCHEMBL21727657 | 0.77 | CYP3A4 (0.55) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| SCHEMBL11209918 | 0.77 | MAOB (0.42) | CA1NFE2L2ALOX5ALDH1A1RELA | |
| SCHEMBL11211999 | 0.77 | MAOB (0.42) | CA1NFE2L2ALOX5ALDH1A1RELA | |
| SCHEMBL11212004 | 0.77 | MAOB (0.42) | CA1NFE2L2ALOX5ALDH1A1RELA | |
| SCHEMBL123485 | 0.76 | ALDH1A1 (0.55) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 | |
| (E)-1,2-Di-P-Tolylethene SCHEMBL1305582 | 0.74 | NFE2L2 (0.74) | CYP3A4CYP2C9CYP2C19CA1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3015263-B1 | LAMINATE, INNER LINER MATERIAL AND PNEUMATIC TIRE | YOKOHAMA RUBBER CO LTD (JP) | 2018-03-28 | — | — | EP | claimed |
| EP-2933098-B1 | LAMINATE, INNER LINER FOR TIRE, AND PNEUMATIC TIRE | YOKOHAMA RUBBER CO LTD (JP) | 2017-08-02 | — | — | EP | claimed |
| EP-1966315-B1 | THERMOPLASTIC METHOD, COMPOSITION, AND ARTICLE | SABIC INNOVATIVE PLASTICS IP (NL) | 2010-12-22 | — | — | EP | claimed |