(E)-1,2-Di-P-Tolylethene

(E)-1,2-Di-P-Tolylethene

SCHEMBL1305582

Cc1ccc(C=Cc2ccc(C)cc2)cc1

nearest known ligand 0.74

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 6/20 0.74
RELA Q04206 1/20 0.67
PTGS1 P23219 2/20 0.61
PTGS2 P35354 2/20 0.61
ALOX5 P09917 1/20 0.61
CA1 P00915 1/20 0.59
CYP2A6 P11509 1/20 0.58
ACHE P22303 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
SMN1; SMN2 Q16637 2/20 0.55
FBP1 P09467 1/20 0.54
TUBB4A P04350 1/20 0.54
TUBB P07437 1/20 0.54
TUBA3C P0DPH7 1/20 0.54
TUBA1B P68363 1/20 0.54
TUBA4A P68366 1/20 0.54
TUBB4B P68371 1/20 0.54
TUBB3 Q13509 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(E)-1,2-Di-P-Tolylethene SCHEMBL1793692 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL318785 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
(E)-1,2-Di-P-Tolylethene SCHEMBL1305580 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL318786 1.00 NFE2L2 (0.74) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL700269 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585865 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL7164327 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585859 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL4585867 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5
SCHEMBL1239547 0.88 NFE2L2 (0.61) NFE2L2RELAPTGS1PTGS2ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0460994-B1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON SA (FR) 1995-03-15 EP claimed
US-5242830-A Detection of impact with fluorescent indicators by embedding microcapsules and releasing HUTCHINSON (FR) 1993-09-07 US claimed
EP-0460994-A1 Method and apparatus to make evident one or more shocks received by a substrate HUTCHINSON S.A. une SociÀ©té Anonyme dotée d'un Conseil de Surveillance et d'un Directoire (FR) 1991-12-11 EP claimed
US-4620055-A Preparation of styrene and stilbene compounds EASTMAN KODAK COMPANY (US) 1986-10-28 US claimed
US-4115464-A DEHYDROGENATION, METAL PHOSPHATE CATALYST THE STANDARD OIL COMPANY (US) 1978-09-19 US claimed
WO-2025063197-A1 CRYSTAL, METHOD FOR PRODUCING CRYSTAL, AND METHOD FOR INDUCING SELF-ORGANIZATION OF SILANOL COMPOUND 国立研究開発法人産業技術総合研究所 2025-03-27 WO disclosed
CN-110799553-B Process for producing polymers 株式会社LG化学 2022-08-16 CN disclosed
US-20220227948-A1 RESIN COMPOSITION PRODUCTION METHOD AND RESIN COMPOSITION SEIKO PMC CORPORATION (JP) 2022-07-21 US disclosed
US-20220081305-A1 CRYSTAL, METHOD OF PRODUCING CRYSTAL, AND METHOD OF SELF-ORGANIZING SILANOL COMPOUND NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2022-03-17 US disclosed
WO-2020085403-A1 CRYSTAL, METHOD FOR PRODUCING CRYSTAL, AND METHOD FOR SELF-ASSEMBLING SILANOL COMPOUNDS 国立研究開発法人産業技術総合研究所 2020-04-30 WO disclosed
CN-107428869-A CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS 巴塞尔聚烯烃意大利有限公司 2017-12-01 CN disclosed
US-9616099-B2 Cyclosporin analogues for preventing or treating hepatitis C infection ENANTA PHARMACEUTICALS, INC. (US) 2017-04-11 US disclosed
EP-0114385-A2 Electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-08-01 EP disclosed
EP-0103868-A2 Improved electrical insulating oil and oil-filled electrical appliances NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1984-03-28 EP disclosed
US-4438021-A THALLIUM AND ZINC OXIDES KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1984-03-20 US disclosed
EP-0062005-A1 Process for the manufacture of styrene and/or stilbene derivatives CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed
EP-0041043-A1 Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene CIBA-GEIGY AG (CH) 1981-12-02 EP disclosed
US-4158099-A FROM SCHIFF BASES AND BIPHENYL COMPOUND CIBA-GEIGY AG (CH) 1979-06-12 US disclosed
US-3991049-A Aromatic compounds containing ethylene double bonds, processes for their manufacture and use CIBA-GEIGY AG (CH) 1976-11-09 US disclosed
US-3946081-A OXIDATION CATALYSTS, GROUP V, VI, OR VII OXIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-23 US disclosed