Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18614729 | 0.88 | CYP1A2 (0.43) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL431857 | 0.85 | HSD17B10 (0.41) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL15067859 | 0.81 | HSD17B10 (0.39) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL8728542 | 0.81 | HSD17B10 (0.42) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL13427886 | 0.78 | KIF11 (0.43) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL297104 | 0.75 | ALDH1A1 (0.56) | CYP1A2CYP2C19CYP2C9HIF1AKIF11 | |
| SCHEMBL2355481 | 0.75 | CYP1A2 (0.59) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL25710684 | 0.75 | HSD17B10 (0.65) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL28108200 | 0.74 | ACP3 (0.46) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 | |
| SCHEMBL5012463 | 0.74 | ACP3 (0.46) | HSD17B10HPGDCYP1A2CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144916-A1 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | The Trustees of the University of Pennsylvania (US) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008124812-A1 | PHEN-NAPHTHALENE AND PHEN-QUINOLINE DERIVATIVES AND THEIR USE FOR BINDING AND IMAGING AMYLOID PLAQUES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2008-10-16 | — | — | WO | disclosed |