Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 2/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 9/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3359501 | 0.87 | ALDH1A1 (0.38) | POLBALDH1A1 | |
| SCHEMBL3353428 | 0.82 | HTR2A (0.54) | POLBHTR2AHTR2CALDH1A1KDM4E | |
| SCHEMBL13308402 | 0.79 | ALDH1A1 (0.39) | POLBALDH1A1KDM4E | |
| SCHEMBL3355499 | 0.76 | ALDH1A1 (0.42) | POLBALDH1A1 | |
| SCHEMBL3355372 | 0.75 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL3356345 | 0.75 | ALDH1A1 (0.37) | POLBALDH1A1KDM4E | |
| SCHEMBL3353011 | 0.74 | LMNA (0.34) | ALDH1A1KDM4E | |
| SCHEMBL3353857 | 0.74 | ALDH1A1 (0.36) | POLBALDH1A1 | |
| SCHEMBL3359150 | 0.73 | ADAMTS5 (0.40) | ALDH1A1 | |
| SCHEMBL3353123 | 0.70 | HTR1A (0.37) | ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068881-A1 | NOVEL BENZODIOXANE AND BENZOXAZINE DERIVATIVES USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-06-17 | — | — | WO | disclosed |