Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.32 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.32 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylpiperazine SCHEMBL9443629 | 0.92 | CHRM5 (0.32) | CHRM5CHRM3OPRD1SIGMAR1 | |
| SCHEMBL9481171 | 0.79 | — | — | |
| SCHEMBL1263669 | 0.78 | POLB (0.38) | CHRM5CHRM3OPRD1SIGMAR1SLC6A2 | |
| SCHEMBL28944208 | 0.78 | CHRM5 (0.36) | CHRM5CHRM3OPRD1SIGMAR1SMN1; SMN2 | |
| SCHEMBL506127 | 0.78 | SIGMAR1 (0.34) | CHRM5CHRM3SIGMAR1GNAI3GNAO1 | |
| SCHEMBL25329312 | 0.77 | GNAO1 (0.53) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL8573059 | 0.77 | GNAO1 (0.53) | SIGMAR1GNAI3GNAO1GNAI1 | |
| SCHEMBL2003708 | 0.77 | ALDH1A1 (0.31) | — | |
| SCHEMBL9317068 | 0.77 | SIGMAR1 (0.37) | CHRM5CHRM3OPRD1SIGMAR1MEN1 | |
| SCHEMBL28366615 | 0.76 | HSD17B10 (0.49) | CHRM5CHRM3SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323814-B1 | Fuel additive compositions containing a Mannich condensation product, a poly(oxyalkylene) monool, and a carboxylic acid | CHEVRON ORONITE CO (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-1375629-B1 | A method of improving the compatibility of a fuel additive composition containing a Mannich condensation product | CHEVRON ORONITE CO (US) | 2009-09-30 | — | — | EP | disclosed |
| US-6749651-B2 | PREVENT AND CONTROL ENGINE DEPOSITS, PARTICULARLY INTAKE VALVE DEPOSITS; IMPROVED COMPATIBILITY | CHEVRON ORONITE COMPANY LLC | 2004-06-15 | — | — | US | disclosed |
| US-6733551-B2 | BLENDING TOGETHER MANNICH CONDENSATION PRODUCT OF HIGH MOLECULAR WEIGHT ALKYL-SUBSTITUTED HYDROXYAROMATIC COMPOUND, AMINE AND ALDEHYDE, HYDROCARBYL-TERMINATED POLY(OXYALKYLENE) MONOOL, CARBOXYLIC ACID, AND SELECTED ANHYDRIDE | CHEVRON ORONITE COMPANY LLC | 2004-05-11 | — | — | US | disclosed |
| EP-1375629-A2 | A method of improving the compatibility of a fuel additive composition containing a Mannich condensation product | Chevron Oronite Company LLC (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20040000089-A1 | Method of improving the compatibility of a fuel additive composition containing a mannich condensation product | CHEVRON ORONITE COMPANY LLC | 2004-01-01 | — | — | US | disclosed |
| US-20030172582-A1 | Fuel additive compositions containing a mannich condensation product, a poly (oxyalkylene) monool, and a carboxylic acid | CHEVRON ORONITE COMPANY LLC | 2003-09-18 | — | — | US | disclosed |
| EP-1323814-A2 | Fuel additive compositions containing a Mannich condensation product, a poly(oxyalkylene) monool, and a carboxylic acid | Chevron Oronite Company LLC (US) | 2003-07-02 | — | — | EP | disclosed |
| EP-0219035-A2 | Process for the preparation of polyamines, and their use in the preparation of polyurethanes | BAYER AG (DE) | 1987-04-22 | — | — | EP | disclosed |