SCHEMBL9317068

SCHEMBL9317068

CC(NC(C)N1CCNCC1)N1CCNCC1

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.37
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
CYP2D6 P10635 1/20 0.33
CYP19A1 P11511 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM1 P11229 1/20 0.33
CYP1A2 P05177 1/20 0.32
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28628160 0.90 CHRM5 (0.37) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL28918485 0.86 CHRM5 (0.35) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL930621 0.82 MEN1 (0.34) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL9540412 0.82 MEN1 (0.34) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL9765922 0.81 OPRD1 (0.33) OPRD1
SCHEMBL3387239 0.80 CHRM5 (0.32) SIGMAR1CHRM5CHRM3
SCHEMBL28204363 0.78 GNAI3 (0.33) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL3389599 0.77 CHRM5 (0.35) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL1303959 0.75 ADH1B (0.37) SIGMAR1MEN1KMT2ACHRM5CHRM3
SCHEMBL1303957 0.75 CHRM5 (0.34) SIGMAR1MEN1KMT2ACHRM5CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11292768-B2 Process for manufacturing chain-extended hydroxyethylethyleneamines, ethyleneamines, or mixtures thereof NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-04-05 US claimed
EP-3596039-B1 PROCESS FOR MANUFACTURING CHAIN-EXTENDED HYDROXYETHYLETHYLENEAMINES, ETHYLENEAMINES, OR MIXTURES THEREOF NOURYON CHEMICALS INT BV (NL) 2021-05-05 EP claimed
US-20200131136-A1 PROCESS FOR MANUFACTURING CHAIN-EXTENDED HYDROXYETHYLETHYLENEAMINES, ETHYLENEAMINES, OR MIXTURES THEREOF NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2020-04-30 US claimed
WO-2018166938-A1 PROCESS FOR MANUFACTURING CHAIN-EXTENDED HYDROXYETHYLETHYLENEAMINES, ETHYLENEAMINES, OR MIXTURES THEREOF AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2018-09-20 WO claimed
US-20160304662-A1 PROCESS FOR FORMING AN ORGANIC POLYMER IN A REACTION OF A POLYENE, AN EPOXY RESIN AND A MIXTURE OF THIOL AND AMINE CURING AGENTS DOW GLOBAL TECHNOLOGIES LLC 2016-10-20 US claimed
US-11390741-B2 Epoxy resin compositions containing an internal mold release agent DOW GLOBAL TECHNOLOGIES LLC (US) 2022-07-19 US disclosed
CN-108602788-B Process for preparing higher ethyleneamines and ethyleneamine derivatives 阿克苏诺贝尔化学品国际有限公司 2022-06-07 CN disclosed
US-11292768-B2 Process for manufacturing chain-extended hydroxyethylethyleneamines, ethyleneamines, or mixtures thereof NOURYON CHEMICALS INTERNATIONAL B.V. (NL) 2022-04-05 US disclosed
US-20220002536-A1 EPOXY RESIN COMPOSITIONS CONTAINING AN INTERNAL MOLD RELEASE AGENT DOW GLOBAL TECHNOLOGIES LLC 2022-01-06 US disclosed
EP-3596039-B1 PROCESS FOR MANUFACTURING CHAIN-EXTENDED HYDROXYETHYLETHYLENEAMINES, ETHYLENEAMINES, OR MIXTURES THEREOF NOURYON CHEMICALS INT BV (NL) 2021-05-05 EP disclosed
EP-3592796-B1 STABLE EPOXY/INTERNAL MOLD RELEASE AGENT BLENDS FOR THE MANUFACTURE OF COMPOSITE ARTICLES DOW GLOBAL TECHNOLOGIES LLC (US) 2021-04-21 EP disclosed
US-20200181361-A1 STABLE EPOXY/INTERNAL MOLD RELEASE AGENT BLENDS FOR THE MANUFACTURE OF COMPOSITE ARTICLES DOW GLOBAL TECHNOLOGIES LLC (US) 2020-06-11 US disclosed
US-20170369635-A1 RAPID-SET EPOXY RESIN SYSTEMS AND PROCESS OF COATING PIPELINES USING THE EPOXY RESIN SYSTEM DOW GLOBAL TECHNOLOGIES LLC (US) 2017-12-28 US disclosed
US-20170029673-A1 POLYURETHANE-ACRYLATE EPOXY ADHESIVE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-02-02 US disclosed
US-20160304662-A1 PROCESS FOR FORMING AN ORGANIC POLYMER IN A REACTION OF A POLYENE, AN EPOXY RESIN AND A MIXTURE OF THIOL AND AMINE CURING AGENTS DOW GLOBAL TECHNOLOGIES LLC 2016-10-20 US disclosed
EP-0629194-A1 CATALYTIC REFORMING OF CYCLIC ALKYLENEAMINES THE DOW CHEMICAL COMPANY (US) 1994-12-21 EP disclosed
EP-0535033-A4 PROCESS OF PREPARING LINEARLY-EXTENDED POLYALKYLENEPOLYAMINES EMPLOYING METAL SILICATE CATALYSTS DOW CHEMICAL CO (US) 1994-05-25 EP disclosed
WO-1993018017-A1 CATALYTIC REFORMING OF CYCLIC ALKYLENEAMINES THE DOW CHEMICAL COMPANY (US) 1993-09-16 WO disclosed
EP-0535033-A1 Process for preparing a linearly-extended polyalkylenepolyamine THE DOW CHEMICAL COMPANY (US) 1993-04-07 EP disclosed
WO-1992000271-A1 PROCESS OF PREPARING LINEARLY-EXTENDED POLYALKYLENEPOLYAMINES EMPLOYING METAL SILICATE CATALYSTS THE DOW CHEMICAL COMPANY (US) 1992-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11292768-B2 Process for manufacturing chain-extended hydroxyethylethyleneamines, ethyleneamines, or mixtures thereof HNMT, PNMT, HRH2 SIGMAR1 224/4885MEN1 2374/4885KMT2A 446/4885
US-20200131136-A1 PROCESS FOR MANUFACTURING CHAIN-EXTENDED HYDROXYETHYLETHYLENEAMINES, ETHYLENEAMINES, OR MIXTURES THEREOF HNMT, PNMT, HRH2 SIGMAR1 224/4885MEN1 2374/4885KMT2A 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.