Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.31 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.31 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903381 | 0.89 | FBP1 (0.33) | POLBMAPK1CES2CES1 | |
| SCHEMBL31121575 | 0.89 | POLB (0.31) | POLBMAPK1CES2CES1 | |
| Bicarbonate SCHEMBL21906199 | 0.81 | MAPK1 (0.36) | POLBMAPK1ALOX5CES2CES1 | |
| SCHEMBL28789053 | 0.79 | ALDH1A1 (0.36) | POLBALDH1A1TDP1 | |
| SCHEMBL5983434 | 0.79 | CRHBP (0.33) | POLBMAPK1CRHBPCRHR2KCNA4 | |
| SCHEMBL27687113 | 0.78 | NPSR1 (0.38) | — | |
| SCHEMBL8655837 | 0.78 | ALDH1A1 (0.35) | POLBMAPK1CRHBPCRHR2KCNA4 | |
| SCHEMBL9186102 | 0.78 | FBP1 (0.37) | POLBALDH1A1TDP1 | |
| SCHEMBL29828470 | 0.78 | KCNA4 (0.31) | KCNA4KCNA1KCNAB1ALDH1A1TDP1 | |
| SCHEMBL28022362 | 0.77 | KCNA4 (0.33) | CRHBPCRHR2KCNA4KCNA1KCNAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805156-B1 | PREPARATION AND USE OF BIPHENYL-4-YL-CARBONYLAMINO ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER HEALTHCARE LLC (US) | 2010-12-22 | — | — | EP | disclosed |
| CN-101583352-A | Preparation and use of biphenyl amino acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2009-11-18 | — | — | CN | disclosed |
| CN-101087769-A | Preparation and use of biphenyl-4-yl-carbonylamino acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORP (US) | 2007-12-12 | — | — | CN | disclosed |
| EP-0670855-A1 | NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1995-09-13 | — | — | EP | disclosed |
| WO-1994012555-A1 | NITRO OR NITROSO GROUP TERMINATED MESOGENIC EPOXY RESIN ADDUCTS | THE DOW CHEMICAL COMPANY (US) | 1994-06-09 | — | — | WO | disclosed |