Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262477 | 0.90 | AURKA (0.45) | RAB9AAURKANPC1KDM4EMAPT | |
| SCHEMBL3260145 | 0.90 | AURKA (0.50) | RAB9AAURKAKDM4EMAPTPTGS2 | |
| SCHEMBL11837070 | 0.81 | KDM4E (0.49) | RAB9AHPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL11831635 | 0.81 | TSHR (0.46) | RAB9ABRAFMAPK14NPC1HPGD | |
| SCHEMBL3263525 | 0.79 | RAB9A (0.43) | RAB9AAURKANPC1GRM4HPGD | |
| SCHEMBL3259619 | 0.79 | RAB9A (0.47) | RAB9AAURKANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11832214 | 0.79 | MAPT (0.56) | RAB9AHPGDSMN1; SMN2HSD17B10KDM4E | |
| SCHEMBL3260509 | 0.76 | L3MBTL1 (0.51) | RAB9AAURKANPC1HPGDSMN1; SMN2 | |
| SCHEMBL11827709 | 0.74 | RAB9A (0.57) | RAB9AAURKANPC1SMN1; SMN2KDM4E | |
| SCHEMBL11827683 | 0.74 | RAB9A (0.64) | RAB9AAURKANPC1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |