Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 4/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263525 | 0.81 | RAB9A (0.43) | RAB9ANPC1NPSR1MAPTHPGD | |
| SCHEMBL3260509 | 0.80 | L3MBTL1 (0.51) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL3390010 | 0.79 | RAB9A (0.49) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL3260403 | 0.77 | NPSR1 (0.62) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL17156327 | 0.77 | ADORA3 (0.48) | RAB9ANPC1KDM4EALDH1A1MAPT | |
| SCHEMBL23403486 | 0.75 | KDM4E (0.50) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL3260145 | 0.74 | AURKA (0.50) | RAB9AKDM4EMAPTAURKADRD2 | |
| SCHEMBL12943711 | 0.73 | KDM4E (0.69) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL24444480 | 0.73 | KDM4E (0.45) | RAB9ANPC1KDM4EALDH1A1NPSR1 | |
| SCHEMBL5403139 | 0.72 | CYP4F2 (0.48) | RAB9ANPC1KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |