Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 4/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17156381 | 0.83 | ADORA3 (0.42) | RAB9ANPC1AURKAMAPK1ADORA3 | |
| SCHEMBL3259619 | 0.81 | RAB9A (0.47) | RAB9ANPC1AURKADGAT1MAPK1 | |
| SCHEMBL3390010 | 0.79 | RAB9A (0.49) | RAB9ANPC1AURKAMAPK1NPSR1 | |
| SCHEMBL3260509 | 0.77 | L3MBTL1 (0.51) | RAB9ANPC1AURKADGAT1MAPK1 | |
| SCHEMBL3260403 | 0.74 | NPSR1 (0.62) | RAB9ANPC1AURKADGAT1MAPK1 | |
| SCHEMBL3260145 | 0.74 | AURKA (0.50) | RAB9AAURKAMAPT | |
| SCHEMBL17156295 | 0.72 | DHODH (0.39) | — | |
| SCHEMBL17156187 | 0.71 | ALKBH1 (0.34) | NPSR1MAPTHPGD | |
| SCHEMBL3262477 | 0.71 | AURKA (0.45) | RAB9ANPC1AURKAMAPT | |
| SCHEMBL23087454 | 0.68 | KDM4E (0.39) | AURKANPSR1ADORA3MAPTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |