Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391740 | 0.87 | PKM (0.42) | PKMPTGS1DGAT1 | |
| SCHEMBL3390287 | 0.85 | EPHX2 (0.40) | PKMDGAT1 | |
| SCHEMBL29864222 | 0.83 | PKM (0.42) | PKMPTGS1 | |
| SCHEMBL27881287 | 0.83 | PTGS1 (0.43) | PKMPTGS1ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL4246326 | 0.81 | PKM (0.36) | PKMPTGS1HPGD | |
| SCHEMBL4252779 | 0.80 | PKM (0.36) | PKMPTGS1NPC1 | |
| SCHEMBL17290871 | 0.78 | BCL2 (0.46) | BCL2MDM2MCL1ALDH1A1HTT | |
| SCHEMBL11650362 | 0.77 | MAPK1 (0.56) | PKMPTGS1BCL2MDM2MCL1 | |
| SCHEMBL3282108 | 0.77 | PTGS1 (0.43) | PTGS1ALDH1A1NPC1HTTSMN1; SMN2 | |
| SCHEMBL3389753 | 0.76 | NPC1 (0.57) | PTGS1BCL2MDM2MCL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |