Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | TRPC3 | Q13507 | 2/20 | 0.34 |
| ▸ | TRPC1 | P48995 | 1/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390256 | 0.87 | PKM (0.46) | PKMDGAT1PTGS1 | |
| SCHEMBL3390287 | 0.84 | EPHX2 (0.40) | PKMEPHX2DGAT1PPARDPPARA | |
| SCHEMBL29864222 | 0.82 | PKM (0.42) | PKMEPHX2PTGS2PTGS1PPARD | |
| SCHEMBL4246326 | 0.80 | PKM (0.36) | PKMEPHX2PTGS2PTGS1TRPC3 | |
| SCHEMBL4252779 | 0.79 | PKM (0.36) | PKMEPHX2PTGS2PTGS1TRPC3 | |
| SCHEMBL13495083 | 0.74 | TGFBR1 (0.48) | PTGS2PTGS1TGFBR1KDM4E | |
| SCHEMBL4253821 | 0.74 | KMT2A (0.43) | PKMEPHX2PTGS2PTGS1GAA | |
| SCHEMBL13702075 | 0.73 | NPC1 (0.38) | PKMEPHX2PTGS2PTGS1KDM4E | |
| SCHEMBL27881287 | 0.70 | PTGS1 (0.43) | PKMPTGS2PTGS1 | |
| SCHEMBL17290871 | 0.65 | BCL2 (0.46) | KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |