Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3390256 | 0.85 | PKM (0.46) | DGAT1PKM | |
| SCHEMBL3391740 | 0.84 | PKM (0.42) | EPHX2DGAT1TGFBR1PKMPPARD | |
| SCHEMBL4246326 | 0.81 | PKM (0.36) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL4252779 | 0.80 | PKM (0.36) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL13495075 | 0.77 | TGFBR1 (0.52) | DGAT1HDAC1HDAC6TGFBR1CYP11B2 | |
| SCHEMBL29864222 | 0.75 | PKM (0.42) | EPHX2CNR1CNR2PKMPPARD | |
| SCHEMBL4253821 | 0.75 | KMT2A (0.43) | EPHX2ALOX5TBXAS1SLC6A3SIGMAR1 | |
| SCHEMBL13702075 | 0.72 | NPC1 (0.38) | EPHX2CNR1CNR2PKM | |
| SCHEMBL12859491 | 0.70 | CNR1 (0.51) | CNR1CNR2TGFBR1CYP11B2CYP3A4 | |
| SCHEMBL12871811 | 0.69 | PTGS2 (0.44) | EPHX2CNR1CNR2TGFBR1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |