SCHEMBL3390530

SCHEMBL3390530

O=C1NCCN1C(=O)c1cccc(C(=O)N2CCNC2=O)c1

nearest known ligand 0.79

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.55
ALDH1A1 P00352 3/20 0.49
GAA P10253 1/20 0.45
NOS1 P29475 1/20 0.45
FAAH O00519 2/20 0.44
NAAA Q02083 1/20 0.44
KDM4E B2RXH2 1/20 0.44
MAPK1 P28482 2/20 0.42
USP2 O75604 1/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
TP53 P04637 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
HSD17B10 Q99714 1/20 0.42
BRD4 O60885 1/20 0.41
GPR6 P46095 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11194139 0.90 MAPT (0.45) MAPTFAAHNAAAKDM4EMEN1
SCHEMBL10832472 0.89 SMN1; SMN2 (0.55) MAPTALDH1A1GAAMAPK1LMNA
SCHEMBL11385930 0.89 PKM (0.51) MAPTALDH1A1KMT2A
SCHEMBL11818563 0.89 HPGD (0.55) MAPTMEN1KMT2AGPR6
SCHEMBL11453383 0.88 L3MBTL3 (0.44) MAPTALDH1A1FAAHNAAAKDM4E
SCHEMBL13432155 0.88 KMT2A (0.48) MAPTALDH1A1GAAKDM4ETSHR
SCHEMBL9037033 0.87 ALDH1A1 (0.58) MAPTALDH1A1GAANOS1KMT2A
SCHEMBL9672850 0.81 MAPT (0.48) MAPTALDH1A1GAAKDM4ENPSR1
SCHEMBL11106868 0.80 STAT3 (0.56) MAPTALDH1A1GAAMAPK1LMNA
SCHEMBL11185619 0.80 MAPT (0.50) MAPTALDH1A1GAANOS1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7683153-B2 Epoxy resin with dibasic acid (methyl ester)/ethyleneurea modifier ARDES ENTERPRISES, INC. (US) 2010-03-23 US claimed
US-20080227950-A1 Latent Epoxy Hardeners Based on Amines Blocked by Acyl-Ethyleneurea, Epoxy Composition Containing the Same and Method of Preparation Thereof ARDES ENTERPRISES, INC. 2008-09-18 US claimed
US-4410689-A MASKED ISOCYANATES THE UPJOHN COMPANY (US) 1983-10-18 US claimed
US-4349663-A Bis(cyclic ureas) monomer compositions useful in making polyurethane polymers THE UPJOHN COMPANY (US) 1982-09-14 US claimed
US-7683153-B2 Epoxy resin with dibasic acid (methyl ester)/ethyleneurea modifier ARDES ENTERPRISES, INC. (US) 2010-03-23 US disclosed
US-7683153-B2 Epoxy resin with dibasic acid (methyl ester)/ethyleneurea modifier ARDES ENTERPRISES, INC. (US) 2010-03-23 US disclosed
US-7683153-B2 Epoxy resin with dibasic acid (methyl ester)/ethyleneurea modifier ARDES ENTERPRISES, INC. (US) 2010-03-23 US disclosed
US-20080227950-A1 Latent Epoxy Hardeners Based on Amines Blocked by Acyl-Ethyleneurea, Epoxy Composition Containing the Same and Method of Preparation Thereof ARDES ENTERPRISES, INC. 2008-09-18 US disclosed
US-20080227950-A1 Latent Epoxy Hardeners Based on Amines Blocked by Acyl-Ethyleneurea, Epoxy Composition Containing the Same and Method of Preparation Thereof ARDES ENTERPRISES, INC. 2008-09-18 US disclosed
US-20080227950-A1 Latent Epoxy Hardeners Based on Amines Blocked by Acyl-Ethyleneurea, Epoxy Composition Containing the Same and Method of Preparation Thereof ARDES ENTERPRISES, INC. 2008-09-18 US disclosed
US-4410689-A MASKED ISOCYANATES THE UPJOHN COMPANY (US) 1983-10-18 US disclosed
US-4349663-A Bis(cyclic ureas) monomer compositions useful in making polyurethane polymers THE UPJOHN COMPANY (US) 1982-09-14 US disclosed