Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | ERN1 | O75460 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601421 | 0.85 | APEX1 (0.39) | CA2CA4 | |
| SCHEMBL3197733 | 0.75 | ERN1 (0.40) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL1045001 | 0.75 | HSD17B10 (0.39) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL20836258 | 0.71 | HSD17B10 (0.37) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL28973883 | 0.70 | TDP1 (0.41) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL11787406 | 0.70 | KLK1 (0.36) | TDP1CYP3A4TSHRHSD17B10ALDH1A1 | |
| SCHEMBL5832081 | 0.70 | MAPK1 (0.58) | TDP1TSHRALOX15ALOX12ALDH1A1 | |
| SCHEMBL9320354 | 0.70 | HSD17B10 (0.36) | TDP1CYP3A4TSHRHSD17B10ALOX15 | |
| SCHEMBL42433 | 0.70 | LMNA (0.45) | TSHRHSD17B10ALOX15ALOX12ALDH1A1 | |
| SCHEMBL3803700 | 0.69 | TDP1 (0.45) | TDP1CYP3A4TSHRHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1394153-B1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | UNIMATEC CO LTD (JP) | 2010-12-29 | — | — | EP | disclosed |
| US-7812157-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2008-09-18 | — | — | US | disclosed |
| US-7384995-B2 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. (JP) | 2008-06-10 | — | — | US | disclosed |
| US-20070155868-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | UNIMATEC CO., LTD. | 2007-07-05 | — | — | US | disclosed |
| US-7199169-B2 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2007-04-03 | — | — | US | disclosed |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | UNIMATEC CO., LTD. (JP) | 2004-08-19 | — | — | US | disclosed |
| EP-1394153-A1 | THIOL COMPOUND DERIVATIVES, HARDENING COMPOSITIONS CONTAINING THESE DERIVATIVES AND MOLDED ARTICLES THEREOF | Unimatec Co., Ltd. (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-3974092-A | COMPOUND, 6B, ORGANOALUMINUM COMPOUND, ETHER OF OLEFIN ALCOHOL | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080227977-A1 | Thiol compound derivative, curable composition containing the derivative, and molded product thereof | TST, CTH, NACA | TDP1 1676/4885CYP3A4 739/4885TSHR 3849/4885 |
| US-20040162368-A1 | Thiol compound derivative, hardening compositions containing these derivatives and molded articles thereof | TST, NACA, CTH | TDP1 1232/4885CYP3A4 1353/4885TSHR 4349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.