SCHEMBL42433

SCHEMBL42433

C=CCOc1c(Br)cc(Br)cc1Br

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HPGD P15428 2/20 0.40
ALDH1A1 P00352 2/20 0.40
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.38
GAA P10253 3/20 0.38
TSHR P16473 1/20 0.38
MEN1 O00255 5/20 0.37
KMT2A Q03164 5/20 0.37
HTT P42858 2/20 0.37
HSD17B10 Q99714 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
ALOX15 P16050 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7600877 0.87 LMNA (0.45) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL13964533 0.87 LMNA (0.43) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL7598077 0.83 LMNA (0.43) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL6578128 0.83 LMNA (0.47) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL2882753 0.82 GAA (0.36) LMNASMN1; SMN2HPGDALDH1A1GAA
SCHEMBL2882749 0.82 GAA (0.36) LMNASMN1; SMN2HPGDALDH1A1GAA
SCHEMBL1445732 0.82 GAA (0.36) LMNASMN1; SMN2HPGDALDH1A1GAA
SCHEMBL10712071 0.80 HRH3 (0.44) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL262332 0.79 MEN1 (0.41) LMNASMN1; SMN2HPGDALDH1A1KDM4E
SCHEMBL10500362 0.79 CA12 (0.45) LMNASMN1; SMN2HPGDALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 231 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4705422-A1 METHOD AND COMPOSITION FOR ANTI-SLIPPING, AND METHOD OF MAKING THEREOF Morehouse School of Medicine (US) 2026-03-11 EP claimed
US-20260062597-A1 METHOD AND COMPOSITION FOR ANTI-SLIPPING, AND METHOD OF MAKING THEREOF MOREHOUSE SCHOOL OF MEDICINE (US) 2026-03-05 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-12379611-B2 Diffractive contact lenses ALCON INC. (CH) 2025-08-05 US claimed
CN-119899344-A Special hydrogenated nitrile rubber for oil field and preparation method thereof 中国石油天然气股份有限公司 2025-04-29 CN claimed
CN-119899342-A Hydrogenated nitrile rubber for special oil field and preparation method thereof 中国石油天然气股份有限公司 2025-04-29 CN claimed
CN-119899334-A Tear-resistant cold-resistant hydrogenated nitrile rubber for oil field and preparation method thereof 中国石油天然气股份有限公司 2025-04-29 CN claimed
CN-118983513-A High-temperature-resistant flame-retardant PVDF-based semi-solid electrolyte and preparation method thereof 华中科技大学 2024-11-19 CN claimed
US-20240368444-A1 METHOD AND COMPOSITION FOR ANTI-SLIPPING, AND METHOD OF MAKING THEREOF MOREHOUSE SCHOOL OF MEDICINE 2024-11-07 US claimed
WO-2024228731-A1 METHOD AND COMPOSITION FOR ANTI-SLIPPING, AND METHOD OF MAKING THEREOF MOREHOUSE SCHOOL OF MEDICINE (US) 2024-11-07 WO claimed
US-20110319580-A1 POLYURETHANE (METH) ACRYLATES USING MODIFIED HYDROXYTHIOLS BANK OF AMERICA, N.A. 2011-12-29 US claimed
CN-100999450-B Preparation technology of polyhalogenated aryl allyl ether compound YANLIN WANG 2010-07-21 CN claimed
CN-100999450-A Preparation technology of polyhalogenated aryl allyl ether compound WANG YANLIN (CN) 2007-07-18 CN claimed
US-6303664-B1 PREPARING PATTERN FOR USE IN METAL CASTINGS BY ADDING HEXABROMOCYCLODODECANE OR TETRABROMOCYCLOOCTANE FLAME RETARDANTS TO VINYL AROMATIC MONOMER; SUSPENDING WATER; ADDING BLOWING AGENT; SEPARATING IMPREGNATED BEADS, WASHING, DRYING STYROCHEM DELAWARE, INC. 2001-10-16 US claimed
EP-0436367-B1 Process for the preparation of fire-retardant expandable thermoplastic beads ARCO CHEM TECH (US) 1995-11-15 EP claimed
US-5106522-A Liquid hydrophobic vehicle for electro-rheological fluid NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) 1992-04-21 US claimed
EP-0436367-A2 Process for the preparation of fire-retardant expandable thermoplastic beads ARCO Chemical Technology, L.P. (US) 1991-07-10 EP claimed
US-5030663-A Heating aqueous suspension of vinylaromatic polymer particles, water, suspending agent, bromophenyl allyl ether, aliphatic hydrocarbon foaming agent ARCO CHEMICAL TECHNOLOGY, INC. (US) 1991-07-09 US claimed
US-4994499-A Polymerizing aqueous suspension of vinyl aromatic monomer, impregnating with blowing agent, heating to polymerize remaining vinyl aromatic monomer, impregnating with flame retardant ARCO CHEMICAL TECHNOLOGY, INC. (US) 1991-02-19 US claimed
US-4168365-A Flame-retardant phenolic resin MATSUSHITA ELECTRIC WORKS, LTD. (JP) 1979-09-18 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062597-A1 METHOD AND COMPOSITION FOR ANTI-SLIPPING, AND METHOD OF MAKING THEREOF GYS1, GYS2, CUTA LMNA 156/4885SMN1; SMN2 823/4885HPGD 4867/4885
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES LBR, CRYZ, CRYAA LMNA 531/4885SMN1; SMN2 4324/4885HPGD 2881/4885
US-20110319580-A1 POLYURETHANE (METH) ACRYLATES USING MODIFIED HYDROXYTHIOLS ESD, MMAB, BHMT2 LMNA 2831/4885SMN1; SMN2 3312/4885HPGD 178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.