Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 2/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL988976 | 0.84 | KMO (0.53) | TDP1CYP3A4CYP1A2HPGDCES2 | |
| SCHEMBL31598432 | 0.84 | KMO (0.53) | TDP1CYP3A4CYP1A2HPGDCES2 | |
| SCHEMBL9340230 | 0.84 | KMO (0.53) | TDP1CYP3A4CYP1A2HPGDCES2 | |
| SCHEMBL21734335 | 0.82 | UNG (0.51) | KMT2AMEN1ALDH1A1TDP1MAOB | |
| SCHEMBL13707523 | 0.82 | MAPT (0.59) | KMT2AALDH1A1TDP1MAOBCYP3A4 | |
| SCHEMBL15656675 | 0.82 | MAPT (0.59) | KMT2AALDH1A1TDP1MAOBCYP3A4 | |
| SCHEMBL8397432 | 0.81 | CA2 (0.59) | ALDH1A1TDP1CYP3A4CES2CES1 | |
| SCHEMBL12621051 | 0.80 | MEN1 (0.55) | KMT2AMEN1ALDH1A1TDP1POLB | |
| SCHEMBL1636978 | 0.80 | ACACB (0.41) | KMT2AMEN1ALDH1A1TDP1MAOB | |
| SCHEMBL6226554 | 0.79 | CA12 (0.56) | KMT2AMEN1ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7910744-B2 | Pyrazole and Pyrimidine groups are introduced on aromatic phosphine; (3-bromophenyl)methyl ketone and ethylene glycol cyclize to [3-(2-methyl-1,3-dioxolane-2-yl)phenyl]diphenylphosphane; adding hydrazine monohydrate, then oxidizing with hydrogen peroxide; [3-(3-Pyrazolyl)phenyl]diphenylphosphane oxide | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENT II KG (DE) | 2011-03-22 | — | — | US | disclosed |
| US-7910744-B2 | Pyrazole and Pyrimidine groups are introduced on aromatic phosphine; (3-bromophenyl)methyl ketone and ethylene glycol cyclize to [3-(2-methyl-1,3-dioxolane-2-yl)phenyl]diphenylphosphane; adding hydrazine monohydrate, then oxidizing with hydrogen peroxide; [3-(3-Pyrazolyl)phenyl]diphenylphosphane oxide | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENT II KG (DE) | 2011-03-22 | — | — | US | disclosed |
| EP-1805193-B1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES | ZYLUM BETEILIGUNGSGMBH & CO PATENTE II KG (DE) | 2010-12-29 | — | — | EP | disclosed |
| EP-1805193-B1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES | ZYLUM BETEILIGUNGSGMBH & CO PATENTE II KG (DE) | 2010-12-29 | — | — | EP | disclosed |
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) | 2008-09-11 | — | — | US | disclosed |
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | ZYLUM BETEILIGUNGSGESELLSCHAFT MBH & CO. PATENTE II KG (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1805193-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES, AND SUBSTITUTED PHOSPHANES PRODUCED ACCORDING TO SAID METHOD | Technische Universität Chemnitz (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006045272-A1 | METHOD FOR THE PRODUCTION OF SUBSTITUTED PHOSPHANES, AND SUBSTITUTED PHOSPHANES PRODUCED ACCORDING TO SAID METHOD | TECHNISCHE UNIVERSITÄT CHEMNITZ (DE) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221335-A1 | Method for the Manufacture of Substituted Phosphanes, and Substituted Phosphanes Manufactured According to Said Method | SCLY, SELENOI, TST | KMT2A 1052/4885MEN1 941/4885ALDH1A1 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.