Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LTA4H | P09960 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.54 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | TLR4 | O00206 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4397448 | 0.96 | TSHR (0.63) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| 1-Propoxy-3-Pentoxybenzene SCHEMBL4568913 | 0.94 | TSHR (0.68) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| 1,3-Dipropoxybenzene SCHEMBL73716 | 0.93 | KMT2A (0.63) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| SCHEMBL15923563 | 0.92 | TSHR (0.71) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| SCHEMBL9487103 | 0.89 | LTA4H (0.68) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| 1-Butyloxy-3-Ethoxybenzene SCHEMBL3459049 | 0.89 | MAPK1 (0.62) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| SCHEMBL11663051 | 0.89 | TSHR (0.72) | TSHRLTA4HKMT2AGPBAR1CYSLTR1 | |
| 1-Butyloxy-3-Methoxybenzene SCHEMBL1071738 | 0.88 | MAPK1 (0.61) | TSHRLTA4HKMT2ACYP1A2CYP2C19 | |
| SCHEMBL3905859 | 0.87 | TSHR (0.76) | TSHRLTA4HGPBAR1CYSLTR1PLA2G4B | |
| SCHEMBL4208924 | 0.87 | TSHR (0.76) | TSHRLTA4HGPBAR1CYSLTR1PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | claimed |
| US-9125406-B2 | Methods and compositions for control of cabbage looper, trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2015-09-08 | — | — | US | disclosed |
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | SIMON FRASER UNIVERSITY (CA) | 2010-07-29 | — | — | US | disclosed |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | SIMON FRASER UNIVERSITY (CA) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131185-A1 | Methods and Compositions for Control of Cabbage Looper, Trichoplusia ni | CDV3, ETV1, BOLA2; BOLA2B | TSHR 1738/4885LTA4H 256/4885KMT2A 36/4885 |
| US-20100190865-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF GYPSY MOTHS, Lymanria dispar | L3MBTL3, L3MBTL4, L3MBTL1 | TSHR 3461/4885LTA4H 38/4885KMT2A 176/4885 |
| US-20100160451-A1 | METHODS AND COMPOSITIONS FOR CONTROL OF CABBAGE LOOPER, Trichoplusia ni | CDV3, ETV1, TMSB4X | TSHR 1753/4885LTA4H 227/4885KMT2A 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.