SCHEMBL3391035

SCHEMBL3391035

CCOc1cccc(-c2ccc([CH]c3ccccc3)cc2)c1OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RELA Q04206 1/20 0.42
PTPRC P08575 1/20 0.41
ALDH1A1 P00352 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
DRD2 P14416 1/20 0.40
DRD1 P21728 1/20 0.40
DRD4 P21917 1/20 0.40
DRD5 P21918 1/20 0.40
DRD3 P35462 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
ADORA2A P29274 1/20 0.40
ADORA1 P30542 1/20 0.40
ENPP1 P22413 1/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MEN1 O00255 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
RECQL P46063 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10595704 0.87 L3MBTL1 (0.47) PTPRCALDH1A1L3MBTL1ADORA3ADORA2A
SCHEMBL4054602 0.87 L3MBTL1 (0.49) PTPRCALDH1A1L3MBTL1ADORA3ADORA2A
SCHEMBL27572284 0.85 L3MBTL1 (0.48) PTPRCALDH1A1L3MBTL1ADORA3ADORA2A
SCHEMBL1882609 0.81 L3MBTL1 (0.47) PTPRCALDH1A1L3MBTL1ADORA3ENPP1
SCHEMBL1568239 0.78 RXRA (0.54) ALDH1A1L3MBTL1MEN1RECQLKMT2A
SCHEMBL29997747 0.78 L3MBTL1 (0.47) PTPRCALDH1A1L3MBTL1ADORA3ADORA2A
SCHEMBL27782420 0.78 SMN1; SMN2 (0.47) ALDH1A1L3MBTL1ADORA3ADORA2AADORA1
SCHEMBL13828076 0.76 ALDH1A1 (0.46) RELAPTPRCALDH1A1L3MBTL1ADORA3
SCHEMBL5255372 0.75 RELA (0.47) RELAALDH1A1L3MBTL1ADORA3ADORA2A
SCHEMBL28424906 0.74 ALDH1A1 (0.42) PTPRCALDH1A1L3MBTL1ADORA3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010027510-A2 ENANTIOSELECTIVE CASCADE MICHAEL-MICHAEL REACTIONS AND RELATED CATALYSTS STC. UNM (US) 2010-03-11 WO claimed