Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.50 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HGFAC | Q04756 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275811 | 1.00 | BCL9 (0.50) | BCL9CTNNB1KMT2APKMGAA | |
| SCHEMBL6707349 | 0.86 | BCL9 (0.49) | BCL9CTNNB1KMT2APKMGAA | |
| SCHEMBL10335399 | 0.86 | BCL9 (0.49) | BCL9CTNNB1KMT2APKMGAA | |
| SCHEMBL28323255 | 0.82 | BCL9 (0.51) | BCL9CTNNB1KMT2APKMGAA | |
| SCHEMBL8740500 | 0.82 | MMP2 (0.53) | BCL9CTNNB1KMT2APKMGAA | |
| SCHEMBL8350753 | 0.82 | RAB9A (0.52) | HTR2AALDH1A1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL9840949 | 0.82 | KMT2A (0.51) | BCL9CTNNB1KMT2AMAPTALDH1A1 | |
| SCHEMBL4423862 | 0.82 | MMP2 (0.53) | BCL9CTNNB1KMT2APKMGAA | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL9840960 | 0.82 | KMT2A (0.51) | BCL9CTNNB1KMT2AMAPTALDH1A1 | |
| SCHEMBL2387943 | 0.82 | MMP2 (0.53) | BCL9CTNNB1KMT2APKMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990614-A | N-heterocyclic amides | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4918107-A | HYDROXYPHENYLACETYL-L-ASPARAGINYL COMPOUNDS | TSUMURA & CO. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0311517-A2 | Amide compound having glutamate receptor inhibiting activity | Takeda Chemical Industries, Ltd. (JP) | 1989-04-12 | — | — | EP | disclosed |