SCHEMBL3391624

SCHEMBL3391624

Nc1ccccc1/C=N/CC/N=C/c1ccccc1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 9/20 0.57
CA12 O43570 8/20 0.57
KDM4E B2RXH2 2/20 0.57
CA9 Q16790 6/20 0.48
CA1 P00915 3/20 0.42
CA7 P43166 1/20 0.42
ALOX15 P16050 2/20 0.39
CYP3A4 P08684 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
GAA P10253 3/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30932838 1.00 CA2 (0.57) CA2CA12KDM4ECA9CA1
SCHEMBL348331 1.00 CA2 (0.57) CA2CA12KDM4ECA9CA1
SCHEMBL28346825 0.90 CA2 (0.47) CA2CA12KDM4ECA9CA1
SCHEMBL866769 0.78 ALOX15 (0.45) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL866768 0.78 ALOX15 (0.45) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL29213057 0.78 ALOX15 (0.45) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL4073613 0.74 HPGD (0.47) KDM4EALOX15CYP3A4CASP1CASP7
SCHEMBL4073609 0.74 HPGD (0.47) KDM4EALOX15CYP3A4CASP1CASP7
SCHEMBL21515952 0.74 CYP3A4 (0.41) KDM4EALOX15CYP3A4CASP1CASP7
SCHEMBL6088736 0.74 HPGD (0.47) KDM4EALOX15CYP3A4CASP1CASP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO claimed
WO-2024255129-A1 RECYCLABLE EPOXY RESIN, SYSTEM MATERIAL AND COMPOSITE MATERIAL THEREOF, AND RECOVERY METHODS THEREFOR 道生天合材料科技(上海)股份有限公司 2024-12-19 WO disclosed
EP-3630784-B1 PREPARATION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2021-07-07 EP disclosed
EP-3630784-A1 PREPARATION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2020-04-08 EP disclosed
US-10266554-B2 Preparation of isocyanatosilanes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-04-23 US disclosed
WO-2018222486-A1 PREPARATION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-12-06 WO disclosed
US-20180346493-A1 PREPARATION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. 2018-12-06 US disclosed
EP-2468801-B1 PROCESS FOR PRODUCING THERMOPLASTIC RESIN COMPOSITION, MOLDED OBJECT, AND LUMINESCENT OBJECT MITSUBISHI RAYON CO (JP) 2017-04-26 EP disclosed
US-8889785-B2 Production method of thermoplastic resin composition, molded body, and light emission body MITSUBISHI RAYON CO., LTD. (JP) 2014-11-18 US disclosed
US-20120214922-A1 PRODUCTION METHOD OF THERMOPLASTIC RESIN COMPOSITION, MOLDED BODY, AND LIGHT EMISSION BODY MITSUBISHI RAYON CO., LTD. (JP) 2012-08-23 US disclosed
US-7741010-B2 Polyester, polyurethane, polyether, polyamide, polyurea formed by a monomer containing two imine groups in the back bone and two end groups containing OH, NR2H, COOH, COCL, COOR, NCO and NCS group polymerized with other monomers; a photolatent or heat latent catalyst such as onium compounds, triazines FUJIFILM CORPORATION (JP) 2010-06-22 US disclosed
US-20080268371-A1 Polyester, polyurethane, polyether, polyamide, polyurea formed by a monomer containing two imine groups in the back bone and two end groups containing OH, NR2H, COOH, COCL, COOR, NCO and NCS group polymerized with other monomers; a photolatent or heat latent catalyst such as onium compounds, triazines FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-20080268371-A1 Polyester, polyurethane, polyether, polyamide, polyurea formed by a monomer containing two imine groups in the back bone and two end groups containing OH, NR2H, COOH, COCL, COOR, NCO and NCS group polymerized with other monomers; a photolatent or heat latent catalyst such as onium compounds, triazines FUJIFILM CORPORATION (JP) 2008-10-30 US disclosed
US-7087669-B2 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-08 US disclosed
US-6951911-B2 Cross-linked polymer and process for producing the same, absorptive structure and absorptive article SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2005-10-04 US disclosed
US-6810575-B1 COMPRISES SUBSTRATE HAVING ON UPPER SURFACE A PLURALITY OF METAL OXIDE NEEDLES EXTENDING UPWARDLY OF SURFACE WITH THEIR CENTRAL AXES PARALLEL WITH EACH OTHER; NEEDLES HAVE SPECIFIC AVERAGE CIRCLE-BASED DIAMETER, ASPECT RATIO; CAPACITOR ASAHI KASAI CHEMICALS CORPORATION (JP) 2004-11-02 US disclosed
US-20040024104-A1 Absorbents and process for producing the same, absorbable constructs and absorbable articles SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2004-02-05 US disclosed
EP-1325777-A1 ABSORBENTS AND PROCESS FOR PRODUCING THE SAME, ABSORBABLE CONSTRUCTS AND ABSORBABLE ARTICLES SANYO CHEMICAL INDUSTRIES, LTD. (JP) 2003-07-09 EP disclosed
US-20030078349-A1 For use in paper diaper, a physiological napkin, a pad, a paper towel TAGAWA DAISUKE (JP) 2003-04-24 US disclosed
EP-1275669-A1 CROSSLINKED POLYMER, PROCESS FOR PRODUCING THE SAME, ABSORBENT STRUCTURE, AND ABSORBENT ARTICLE SANYO CHEMICAL INDUSTRIES, Ltd. (JP) 2003-01-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180346493-A1 PREPARATION OF ISOCYANATOSILANES IDH3A, IDH2, IDH1 CA2 922/4885CA12 774/4885KDM4E 1663/4885
US-10266554-B2 Preparation of isocyanatosilanes IDH3A, IDH2, IDH1 CA2 922/4885CA12 774/4885KDM4E 1663/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.