Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.42 |
| ▸ | GRM5 | P41594 | 6/20 | 0.37 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392062 | 0.90 | KCNH2 (0.54) | KCNH2TGFBR1GRM5METAP2METAP1 | |
| SCHEMBL3393142 | 0.84 | CYP19A1 (0.41) | KCNH2 | |
| SCHEMBL3397575 | 0.81 | KCNH2 (0.43) | KCNH2TGFBR1EGLN2 | |
| SCHEMBL3395600 | 0.81 | L3MBTL1 (0.35) | KCNH2TGFBR1GRM5METAP2METAP1 | |
| SCHEMBL3397038 | 0.80 | KCNH2 (0.42) | KCNH2TGFBR1GRM5EGLN2 | |
| SCHEMBL3393337 | 0.77 | KCNH2 (0.58) | KCNH2TGFBR1GRM5CRHR1 | |
| SCHEMBL3397167 | 0.77 | KCNH2 (0.42) | KCNH2EGLN2 | |
| SCHEMBL3399143 | 0.76 | KCNH2 (0.41) | KCNH2EGLN2 | |
| SCHEMBL3392275 | 0.76 | KCNH2 (0.46) | KCNH2TGFBR1GRM5METAP2METAP1 | |
| SCHEMBL3434735 | 0.76 | KCNH2 (0.40) | KCNH2TGFBR1EGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010046780-A2 | ANTI VIRAL COMPOUNDS | INSTITUT PASTEUR KOREA (KR) | 2010-04-29 | — | — | WO | disclosed |