Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | DRD5 | P21918 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3394621 | 0.85 | FAAH (0.39) | FAAHEPHX2SLC6A4SLC6A3GRM2 | |
| SCHEMBL13070020 | 0.79 | MBTD1 (0.51) | TEAD1BCHEACHEBACE1 | |
| SCHEMBL3713843 | 0.76 | GRM2 (0.37) | FAAHEPHX2GRM2 | |
| SCHEMBL3393472 | 0.75 | MAOB (0.50) | FAAHEPHX2DRD2 | |
| Trifluoroacetic Acid SCHEMBL3392279 | 0.72 | EPHX2 (0.36) | FAAHEPHX2GRM2SCN9A | |
| SCHEMBL3398473 | 0.72 | TEAD1 (0.57) | GRM2TEAD1BCHEACHEBACE1 | |
| SCHEMBL19538689 | 0.70 | TSHR (0.60) | FAAHEPHX2GRM2BCHEACHE | |
| SCHEMBL3715589 | 0.69 | GRM2 (0.37) | EPHX2GRM2HRH3DRD2HTR1A | |
| SCHEMBL17878028 | 0.68 | FAAH (0.53) | FAAHGRM2SCN9ADRD2DRD3 | |
| SCHEMBL4564168 | 0.66 | L3MBTL1 (0.47) | FAAHEPHX2SLC6A4GRM2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2246329-A1 | 4(1H)-pyridinone derivatives and their use as antimalaria agents | Glaxo Group Limited (GB) | 2010-11-03 | — | — | EP | disclosed |