Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL699638 | 0.86 | CTRB1 (0.33) | FASNCTRB1 | |
| SCHEMBL16398956 | 0.83 | TDP1 (0.44) | FASNCTRB1 | |
| SCHEMBL632476 | 0.83 | HTR2A (0.44) | FASN | |
| SCHEMBL16398868 | 0.81 | TP53 (0.41) | FASNCTRB1 | |
| SCHEMBL17512439 | 0.81 | CALM1 (0.39) | FASNCTRB1 | |
| SCHEMBL6076922 | 0.79 | TSHR (0.40) | FASNCTRB1 | |
| SCHEMBL2798213 | 0.77 | CA2 (0.38) | FASN | |
| SCHEMBL1698739 | 0.75 | AKR1B1 (0.46) | CTRB1 | |
| SCHEMBL1684322 | 0.75 | ALDH1A1 (0.33) | FASNCTRB1 | |
| SCHEMBL4456540 | 0.75 | MAOB (0.31) | FASNCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | claimed |
| EP-3022199-A1 | CYANOTRIAZOLE COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2016-05-25 | — | — | EP | disclosed |
| WO-2015008872-A1 | CYANOTRIAZOLE COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-01-22 | — | — | WO | disclosed |
| EP-1716160-B1 | NOVEL INHIBITORS OF CHYMASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-29 | — | — | EP | disclosed |