Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340676 | 0.89 | TSHR (0.43) | ALDH1A1TSHRKMT2AHTTPDK1 | |
| SCHEMBL31372250 | 0.88 | KMT2A (0.49) | ALDH1A1TSHRKMT2AMEN1HPGD | |
| SCHEMBL18360184 | 0.88 | KMT2A (0.49) | ALDH1A1TSHRKMT2AMEN1HPGD | |
| SCHEMBL339506 | 0.86 | PARP10 (0.50) | ALDH1A1TSHRKMT2APOLBMAPT | |
| SCHEMBL340328 | 0.85 | MAPT (0.44) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL18360185 | 0.82 | HDAC1 (0.42) | ALDH1A1KMT2APOLBMEN1MAPT | |
| SCHEMBL340375 | 0.82 | ELANE (0.51) | ALDH1A1MAPTHPGDHIF1AKDM4E | |
| SCHEMBL3274226 | 0.81 | RORC (0.63) | ALDH1A1POLBRORC | |
| SCHEMBL31372553 | 0.79 | HDAC6 (0.48) | ALDH1A1TSHRMAPTHDAC6 | |
| SCHEMBL3279217 | 0.79 | RORC (0.50) | ALDH1A1KMT2APOLBMEN1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288576-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2012-10-16 | — | — | US | disclosed |
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZANNAN SCITECH CO., LTD. (CN) | 2012-01-19 | — | — | US | disclosed |
| US-8049025-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2011-11-01 | — | — | US | disclosed |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZHENG-YUN JAMES ZHAN (CN) | 2010-02-18 | — | — | US | disclosed |
| US-7632772-B2 | Recyclable ruthenium catalysts for metathesis reactions | Zhan, Zheng-Yun James (CN) | 2009-12-15 | — | — | US | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | ALDH1A1 2069/4885TSHR 3747/4885KMT2A 3126/4885 |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | ALDH1A1 2069/4885TSHR 3747/4885KMT2A 3126/4885 |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | RPIA, REV1, RCSD1 | ALDH1A1 2069/4885TSHR 3747/4885KMT2A 3126/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.