Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340676 | 0.88 | TSHR (0.43) | PARP10PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8327603 | 0.86 | PARP10 (0.51) | PARP10IRAK4TOP2APOLBMAPK1 | |
| SCHEMBL339283 | 0.86 | ALDH1A1 (0.49) | POLBPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL31372250 | 0.86 | KMT2A (0.49) | MAPK1ALDH1A1LMNAHTTPDK1 | |
| SCHEMBL18360184 | 0.86 | KMT2A (0.49) | MAPK1ALDH1A1LMNAHTTPDK1 | |
| SCHEMBL18360185 | 0.84 | HDAC1 (0.42) | POLBMAPK1ALDH1A1MAPTHTT | |
| SCHEMBL340328 | 0.84 | MAPT (0.44) | MAPK1ALDH1A1LMNAMAPTALOX12 | |
| SCHEMBL340375 | 0.81 | ELANE (0.51) | MAPK1ALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7325813 | 0.80 | PARP10 (0.59) | PARP10IRAK4TOP2APOLBMAPK1 | |
| SCHEMBL3827746 | 0.78 | P2RX3 (0.41) | IRAK4POLBLMNAKMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288576-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2012-10-16 | — | — | US | disclosed |
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZANNAN SCITECH CO., LTD. (CN) | 2012-01-19 | — | — | US | disclosed |
| US-8049025-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2011-11-01 | — | — | US | disclosed |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZHENG-YUN JAMES ZHAN (CN) | 2010-02-18 | — | — | US | disclosed |
| US-7632772-B2 | Recyclable ruthenium catalysts for metathesis reactions | Zhan, Zheng-Yun James (CN) | 2009-12-15 | — | — | US | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | PARP10 340/4885IRAK4 1573/4885TOP2A 3386/4885 |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | PARP10 340/4885IRAK4 1573/4885TOP2A 3386/4885 |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | RPIA, REV1, RCSD1 | PARP10 340/4885IRAK4 1573/4885TOP2A 3386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.