Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 7/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | CENPE | Q02224 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340676 | 0.93 | TSHR (0.43) | ELANEPTGS1PTGS2CYP1A2CYP2C19 | |
| SCHEMBL18360184 | 0.85 | KMT2A (0.49) | HPGDHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL31372250 | 0.85 | KMT2A (0.49) | HPGDHDAC1HDAC8HDAC6ALDH1A1 | |
| SCHEMBL339283 | 0.82 | ALDH1A1 (0.49) | HPGDHDAC1HDAC8HDAC6MAPT | |
| SCHEMBL339506 | 0.81 | PARP10 (0.50) | HDAC1HDAC8HDAC6MAPTSMN1; SMN2 | |
| SCHEMBL340328 | 0.80 | MAPT (0.44) | HPGDHDAC1HDAC8HDAC6MAPT | |
| SCHEMBL18360185 | 0.78 | HDAC1 (0.42) | CYP1A2CYP2D6CYP2C19HDAC1HDAC8 | |
| SCHEMBL31372553 | 0.75 | HDAC6 (0.48) | CYP1A2CYP2D6CYP2C19HDAC6MAPT | |
| SCHEMBL4262890 | 0.74 | PTGS2 (0.45) | PTGS1PTGS2CYP1A2SLC22A6 | |
| SCHEMBL15998600 | 0.74 | CNR2 (0.37) | CYP1A2CYP2C19HDAC1HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1827688-B1 | NOVEL METATHESIS RUTHENIUM CATALYST | BOEHRINGER INGELHEIM INT (DE) | 2014-09-03 | — | — | EP | disclosed |
| US-8288576-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2012-10-16 | — | — | US | disclosed |
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZANNAN SCITECH CO., LTD. (CN) | 2012-01-19 | — | — | US | disclosed |
| US-8049025-B2 | Recyclable ruthenium catalysts for metathesis reactions | ZANNAN SCITECH CO., LTD. (CN) | 2011-11-01 | — | — | US | disclosed |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | ZHENG-YUN JAMES ZHAN (CN) | 2010-02-18 | — | — | US | disclosed |
| US-7632772-B2 | Recyclable ruthenium catalysts for metathesis reactions | Zhan, Zheng-Yun James (CN) | 2009-12-15 | — | — | US | disclosed |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | ZHENG-YUN JAMES ZHAN (CN) | 2007-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016093-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | ELANE 1426/4885PTGS1 1487/4885PTGS2 528/4885 |
| US-20100041844-A1 | RECYCLABLE RUTHENIUM CATALYSTS FOR METATHESIS REACTIONS | RPIA, REV1, RCSD1 | ELANE 1426/4885PTGS1 1487/4885PTGS2 528/4885 |
| US-20070043180-A1 | Recyclable ruthenium catalysts for metathesis reactions | RPIA, REV1, RCSD1 | ELANE 1426/4885PTGS1 1487/4885PTGS2 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.