Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A2 | O15244 | 2/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 5/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 5/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | STAT6 | P42226 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8148766 | 0.75 | — | — | |
| SCHEMBL870113 | 0.72 | GRIN2D (0.46) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL3334426 | 0.72 | SLC22A2 (0.37) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| Phosphine SCHEMBL25171299 | 0.72 | SLC22A2 (0.37) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL498011 | 0.72 | SLC22A2 (0.37) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL1697138 | 0.72 | LMNA (0.33) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL3284553 | 0.70 | LMNA (0.35) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL1015951 | 0.70 | GRIN2D (0.38) | SLC22A2SLC47A1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL15467179 | 0.70 | GRIN2D (0.38) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B | |
| SCHEMBL10415085 | 0.70 | GRIN2D (0.39) | SLC22A2SLC47A1MAPTGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240376055-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-14 | — | — | US | claimed |
| EP-2817003-A1 | COMPOUNDS FOR TREATING PARVOVIRUS INFECTION | Aratana Therapeutics NV (BE) | 2014-12-31 | — | — | EP | disclosed |
| WO-2013124403-A1 | COMPOUNDS FOR TREATING PARVOVIRUS INFECTION | OKAPI SCIENCES NV (BE) | 2013-08-29 | — | — | WO | disclosed |
| EP-1487802-B1 | 2,3-Diaryl-pyrazolidine derivatives as neurotensin degrading enzyme inhibitors | ABBOTT HEALTHCARE PRODUCTS BV (NL) | 2010-12-29 | — | — | EP | disclosed |
| US-7186741-B2 | Neurotensin active 2,3,diaryl-pyrazolidine derivatives | SOLVAY PHARMACEUTICALS B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| EP-1684715-A2 | COMPOSITIONS COMPRISING CYCLOHEXYLAMINES AND AMINOADAMANTANES | Merz Pharma GmbH & Co. KGaA (DE) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005044228-A2 | COMPOSITIONS COMPRISING CYCLOHEXYLAMINES AND AMINOADAMANTANES | MERZ PHARMA GMBH & CO. KGAA (DE) | 2005-05-19 | — | — | WO | disclosed |
| EP-1487802-A1 | NEUROTENSIN ACTIVE 2,3-DIARYL-PYRAZOLIDINE DERIVATIVES | Solvay Pharmaceuticals B.V. (NL) | 2004-12-22 | — | — | EP | disclosed |
| US-20040242493-A1 | Neurotensin active 2,3,diaryl-pyrazolidine derivatives | ABBVIE B.V. (NL) | 2004-12-02 | — | — | US | disclosed |
| WO-2003078400-A1 | NEUROTENSIN ACTIVE 2,3-DIARYL-PYRAZOLIDINE DERIVATIVES | SOLVAY PHARMACEUTICALS B.V. (NL) | 2003-09-25 | — | — | WO | disclosed |
| EP-0029658-A1 | Salts of dihalo-2-quinoxaline carboxylic acids, their preparation and pharmaceutical formulations containing them | ELI LILLY AND COMPANY (US) | 1981-06-03 | — | — | EP | disclosed |
| US-4252954-A | VIRICIDES | ELI LILLY AND COMPANY (US) | 1981-02-24 | — | — | US | disclosed |
| US-4061774-A | Halogenated amino methyl adamantane derivatives | LILLY INDUSTRIES, LIMITED (EN) | 1977-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242493-A1 | Neurotensin active 2,3,diaryl-pyrazolidine derivatives | NTSR1, NTSR2, NPY1R | SLC22A2 2611/4885SLC47A1 641/4885MAPT 2664/4885 |
| US-20240376055-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | SLC22A2 1044/4885SLC47A1 997/4885MAPT 989/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.