Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.41 |
| ▸ | HTR3B | O95264 | 1/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898137 | 0.78 | C1S (0.46) | C1SPARP1HTR3EHTR3BHTR3A | |
| SCHEMBL19371450 | 0.77 | C1S (0.44) | C1SPARP1HTR3EHTR3BHTR3A | |
| SCHEMBL3388884 | 0.76 | HTR3E (0.68) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5557095 | 0.76 | SIGMAR1 (0.47) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL15229159 | 0.76 | PARP1 (0.42) | PARP1HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL3389328 | 0.74 | IDO1 (0.42) | C1SALDH1A1MAPK1SMN1; SMN2IDO1 | |
| SCHEMBL1797820 | 0.73 | ALDH1A1 (0.58) | C1SHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL36862 | 0.73 | ALDH1A1 (0.58) | C1SHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7529429 | 0.73 | ALDH1A1 (0.58) | C1SHTR3EHTR3BHTR3AHTR3D | |
| Benzene SCHEMBL27899224 | 0.73 | ALDH1A1 (0.58) | C1SHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010048164-A2 | N,N'-DI-P-BROMOPHENYL GUANIDINE TREATMENT FOR STROKE AT DELAYED TIMEPOINTS | UNIVERSITY OF SOUTH FLORIDA (US) | 2010-04-29 | — | — | WO | claimed |